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4.4.1.17: Holocytochrome-c synthase

This is an abbreviated version!
For detailed information about Holocytochrome-c synthase, go to the full flat file.

Word Map on EC 4.4.1.17

Reaction

Holocytochrome c
=
apocytochrome c
+
heme

Synonyms

CCHL, ccsA1, cyc2p, CYC3, cytochrome c heme lyase, Cytochrome c heme-lyase, Cytochrome c synthase, HCC synthase, HCCH, HCCS, heme lyase, holocytochrome c synthase, Holocytochrome c synthetase, Holocytochrome c-type synthase, Holocytochrome-C synthase, Holocytochrome-C-type synthase, Synthetase, holocytochrome c, System III

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.17 Holocytochrome-c synthase

Activating Compound

Activating Compound on EC 4.4.1.17 - Holocytochrome-c synthase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cytosolic factor
-
requirement
-
glutathione
-
activation
NADH
-
10fold activation between 1 and 10 mM of NADH
NADPH
-
about half of the activation observed with NADH
additional information
-
independent of a potential across the inner mitochondrial membrane generated by N,N,N',N'-tetramethyl-p-phenylenediamine/ascorbate
-