Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.4.1.15: D-cysteine desulfhydrase

This is an abbreviated version!
For detailed information about D-cysteine desulfhydrase, go to the full flat file.

Word Map on EC 4.4.1.15

Reaction

D-cysteine
+
H2O
=
Sulfide
 +
NH3
 +
pyruvate

Synonyms

cysteine desulfhydrase, D-CDes, D-cysteine desulfhydrase, D-cysteine lyase, DCD, DCyD

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.15 D-cysteine desulfhydrase

Specific Activity

Specific Activity on EC 4.4.1.15 - D-cysteine desulfhydrase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.001594
-
D-cysteine desulfhydrase activity in WT
0.012
-
growth of the bacteria with methionine as sulfur source
0.0123
-
after partial purification
0.018
0.02
-
growth of the bacteria with MgSO4 and p-nitrophenlysulfate as sulfur source
0.022
-
growth of the bacteria with MgSO4 as sulfur source
0.03
-
growth of the bacteria with MgSO4 and Na2S2O3 as sulfur source
0.035
-
growth of the bacteria with reduced glutathione as sulfur source
0.0356
-
D-cysteine desulfhydrase activity in mutant E295S
0.1475
-
D-cysteine desulfhydrase activity in double mutant E295S/L322T
0.21
-
purified enzyme, 37°C, pH 9.0
0.6653
D-cysteine desulfhydrase activity in mutant T386L. Changing the threonine 386 residue alone reduces the activity of the enzyme substantially of about 11.5% of the native recombinant enzyme, although it does not cause complete loss of activity.
13
-
purified enzyme, 30°C, pH 8.0, with D-cysteine as substrate
5.784
D-cysteine desulfhydrase activity in wild-type
56.3
-
purified enzyme, 30°C, pH 8.0, with 3-chloro-D-alanine as substrate
additional information