4.4.1.14: 1-aminocyclopropane-1-carboxylate synthase

This is an abbreviated version!
For detailed information about 1-aminocyclopropane-1-carboxylate synthase, go to the full flat file.

Reaction

Synonyms

1-aminocyclopropane carboxylic acid synthase, 1-aminocyclopropane-1-carboxylate synthase, 1-aminocyclopropane-1-carboxylate synthase 4, 1-aminocyclopropane-1-carboxylate synthase 6, 1-aminocyclopropane-1-carboxylate synthetase, 1-aminocyclopropane-1-carboxylic acid synthase, 1-aminocyclopropanecarboxylate synthase, ACACS2 gene, ACC synthase, ACS, ACS-1, ACS1, ACS2, ACS3, ACS4, ACS5, ACS6, ACS7, ACS9, aminocyclopropane-1-carboxylate synthase, aminocyclopropane-2-carboxylic acid synthase, aminocyclopropanecarboxylate synthase, aminocyclopropanecarboxylic acid synthase, ASC, AtACS4 gene, Ca-ACS1, CyACS1, DC-ACS1, DC-ACS2, GhACS1, LE-ACS1A, LE-ACS2, LE-ACS3, LE-ACS4, LE-ACS6, LeACS2, MA-ACS4, MdACS1, MdACS3, MdACS5B, OsACS1, PgACS1, PgACS2, PgACS3a, PgACS3b, PgACS4, PmACS2, PmACS3, PmACS4, Pp-ACS1, S-adenosyl-L-methionine methylethioadenosine-lyase, S-adenosyl-L-methionine methylthioadenosine-lyase, S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming), synthase, 1-aminocyclopropanecarboxylate, type 2 1-aminocyclopropane-1-carboxylate synthase, type-2 ACC synthase

ECTree

     4 Lyases

         4.4 Carbon-sulfur lyases

             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)

                4.4.1.14 1-aminocyclopropane-1-carboxylate synthase

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Results	in table
39	Activating Compound
279	AA Sequence
21	Application
1	CAS Registry Number
42	Cloned(Commentary)
47	Cofactor
7	Crystallization (Commentary)
7	Expression
15	General Information
2	General Stability
4	IC50 Value
68	Inhibitors
2	Ki Value [mM]
54	KM Value [mM]
3	Localization
1	Metals/Ions
49	Molecular Weight [Da]
58	Natural Substrates/ Products (Substrates)
157	Organism
5	Pathway
15	PDB ID
9	pH Optimum
4	pH Range
1	pH Stability
31	pI Value
7	Posttranslational Modification
40	Protein Variants
35	Purification (Commentary)
3	Reaction
24	Reaction Type
138	Reference
1	Renatured (Commentary)
116	Source Tissue
20	Specific Activity [micromol/min/mg]
4	Storage Stability
112	Substrates and Products (Substrate)
41	Subunits
214	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
4	Temperature Stability [°C]
26	Turnover Number [1/s]

KM Value

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KM Value on EC 4.4.1.14 - 1-aminocyclopropane-1-carboxylate synthase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.02

(-)-S-adenosyl-L-methionine

Solanum lycopersicum

-

-

34569

0.037

(R,S)-S-adenosyl-L-methionine

Malus domestica

-

beta,gamma-elimination

649492

0.037

(R,S)-S-adenosylmethionine

Malus domestica

-

beta,gamma-elimination

650026

0.012

(S,S)-S-adenosyl-L-methionine

Malus domestica

-

alpha,gamma-elimination

649492

0.026

(S,S)-S-adenosylmethionine

Malus domestica

-

alpha,gamma-elimination

650026

37

alanine

Malus domestica

-

transamination

650026

35

L-alanine

Malus domestica

-

transamination

649492, 649945

40

L-arginine

Malus domestica

-

transamination

649945

0.27 - 1.4

L-Vinylglycine

4 entries

0.01 - 1.4

S-adenosyl-L-methionine

38 entries

4.1

S-methyl-L-methionine

Malus domestica

-

beta,gamma-elimination

649492

0.27

L-Vinylglycine

Malus domestica

-

deamination

650026

1.4

L-Vinylglycine

Malus domestica

-

-

649958

1.4

L-Vinylglycine

Malus domestica

-

alpha-ketobutyrate production

649492

1.4

L-Vinylglycine

Malus domestica

-

deamination

649945

0.01

S-adenosyl-L-methionine

Diospyros kaki

-

pH 8.5, 30°C

659653

0.012

S-adenosyl-L-methionine

Malus sylvestris

-

-

34588

0.012

S-adenosyl-L-methionine

Malus domestica

-

elimination

649945

0.0133

S-adenosyl-L-methionine

Cucurbita maxima

-

-

34572

0.017

S-adenosyl-L-methionine

Cucurbita pepo

-

-

34583

0.02

S-adenosyl-L-methionine

Solanum lycopersicum

-

-

34567, 34577, 34581

0.023

S-adenosyl-L-methionine

Cucurbita pepo

P23279

refolded enzyme

34582

0.02927

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of xanthine–xanthine oxidase and catalase

682367

0.0315

S-adenosyl-L-methionine

Solanum lycopersicum

-

30°C, pH 8.5, wild-type enzyme

665869

0.03168

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

8 h after chilling

682367

0.03213

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of xanthine–xanthine oxidase

682367

0.03565

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of methylviologen and catalase

682367

0.03608

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of methylviologen

682367

0.038 - 0.167

S-adenosyl-L-methionine

Solanum lycopersicum

-

Km increases from pH 7.5 to 9.5

34565

0.03977

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

8 h after chilling in the presence of catalase

682367

0.03977

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

8 h after chilling in the presence of n-propyl gallate

682367

0.04

S-adenosyl-L-methionine

Solanum lycopersicum

-

-

34569

0.04

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

3 h after chilling

682367

0.04056

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

8 h after chilling in the presence of superoxide dismutase

682367

0.04098

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of xanthine–xanthine oxidase and superoxide dismutase

682367

0.04101

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

12 h after chilling

682367

0.04136

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of methylviologen and superoxide dismutase

682367

0.04208

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of xanthine–xanthine oxidase and n-propyl gallate

682367

0.04216

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of xanthine–xanthine oxidase and 1,4-diazabicyclo(2,2,2) octane

682367

0.04322

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of methylviologen and 1,4-diazabicyclo(2,2,2) octane

682367

0.04438

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of methylviologen and n-propyl gallate

682367

0.04443

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

8 h after chilling in the presence of 1,4-diazabicyclo(2,2,2) octane

682367

0.0458

S-adenosyl-L-methionine

Solanum lycopersicum

-

30°C, pH 8.5, mutant enzyme Y151F

665869

0.05232

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

-

682367

0.055

S-adenosyl-L-methionine

Vigna radiata

-

-

34566

0.056

S-adenosyl-L-methionine

Dianthus caryophyllus

-

recombinant enzyme, pH 8.5, 30°C

730269

0.05712

S-adenosyl-L-methionine

Vigna radiata var. radiata

-

without chilling in the presence of H2O2

682367

0.12

S-adenosyl-L-methionine

Solanum lycopersicum

-

-

653505

0.12

S-adenosyl-L-methionine

Cucurbita maxima

-

-

34572

0.168

S-adenosyl-L-methionine

Solanum lycopersicum

-

30°C, pH 8.5, mutant enzyme Y151G

665869

0.409

S-adenosyl-L-methionine

Solanum lycopersicum

-

30°C, pH 8.5, mutant enzyme Y151F/Y152F

665869

0.514

S-adenosyl-L-methionine

Solanum lycopersicum

-

30°C, pH 8.5, mutant enzyme Y152F

665869

1.4

S-adenosyl-L-methionine

Penicillium citrinum

-

pH 9.0, 30°C

650624