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4.4.1.11: methionine gamma-lyase

This is an abbreviated version!
For detailed information about methionine gamma-lyase, go to the full flat file.

Word Map on EC 4.4.1.11

Reaction

L-methionine
+
H2O
=
methanethiol
 +
NH3
 +
2-oxobutanoate

Synonyms

CalE6, EhMGL1, EhMGL2, fer1MgL2, Fn1419, L-methionase, L-methioninase, L-methionine gamma-lyase, L-methionine gamma-lyase 1, L-methionine-alpha-deamino-gamma-mercaptomethane lyase, L-methionine-alpha-deamino-gamma-mercaptomethane-lyase, L-methionine-gamma-lyase, lyase, methionine, MdeA, MegL, METase, methioninase, methionine alpha,gamma-lyase, methionine dethiomethylase, methionine gamma-lyase, methionine lyase, methionine-gamma-lyase, MGL, MGL1, MGL2, rMETase, sav7062, TvMGL1, TvMGL2, YtjE

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.11 methionine gamma-lyase

Specific Activity

Specific Activity on EC 4.4.1.11 - methionine gamma-lyase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0013
-
in citrate phosphate buffer, pH 7.0, at 30°C
0.0014
0.0015
0.0016
-
in citrate phosphate buffer, pH 7.0, at 30°C
0.0017
0.0019
0.002
0.0021
-
in citrate phosphate buffer, pH 7.0, at 30°C
0.0023
-
in citrate phosphate buffer, pH 7.0, at 30°C
0.0026
-
in citrate phosphate buffer, pH 7.0, at 30°C
0.0028
0.003
-
in citrate phosphate buffer, pH 7.0, at 30°C
0.173
-
coconut seed as solid substrate
0.215
-
cotton seed as solid substrate
0.235
-
rice bran as solid substrate
0.328
-
wheat flour as solid substrate
0.36
recombinant EhMGL1
0.44
recombinant EhMGL2
0.536
-
lentil hulls as solid substrate
0.62
-
wheat bran as solid substrate
0.63
-
broad bean as solid substrate
0.67
-
chicken feathers as solid substrate
0.723
-
suya bean as solid substrate
10
purified enzyme
10.2
-
purified recombinant enzyme, pH 8.0, 30°C, substrate L-methionine
108
-
pH not specified in the publication, temperature not specified in the publication
11
-
after treatment with PEG
12.8
-
purified His-tagged recombinant enzyme, pH 8.0, 30°C, substrate L-methionine
123
wild-type enzyme, substrate L-cystine, without nisin induction
14
recombinant enzyme, substrate L-cystathionine, without nisin induction
16.6
-
purified His-tagged recombinant enzyme, pH 8.0, 30°C, substrate L-methionine
19
recombinant enzyme, substrate L-cystine or L-methionine, without nisin induction
3.25
mutant Y58F, pH 8.0, 30°C
41
-
after DTT treatment
44
-
methoxypolyethylene glycol succinimidyl glutarate 5000 treated recombinant METase
5
-
purified His-tagged recombinant enzyme, pH 8.0, 30°C, substrate L-methionine
54
-
crystals
60
wild-type enzyme, substrate L-cystathionine, without nisin induction
90
wild-type enzyme, substrate L-methionine, without nisin induction
additional information