4.3.2.6: gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase
This is an abbreviated version!
For detailed information about gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase, go to the full flat file.
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Synonyms
btrG, gamma-glutamyl cyclotransferase, GGC
ECTree
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Systematic Name
Systematic Name on EC 4.3.2.6 - gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase
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gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase (5-oxoproline producing)
The enzyme catalyses the last step in the biosynthesis of the aminoglycoside antibiotic butirosin B. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the alpha-amine of the terminal gamma-L-glutamate of the side chain, releasing it as the cyclic 5-oxo-L-proline.