4.3.2.4: purine imidazole-ring cyclase

This is an abbreviated version!
For detailed information about purine imidazole-ring cyclase, go to the full flat file.

Reaction

Synonyms

cyclase, purine imidazole ring, PurIR cyclase

ECTree

     4 Lyases

         4.3 Carbon-nitrogen lyases

             4.3.2 Amidine-lyases

                4.3.2.4 purine imidazole-ring cyclase

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1	CAS Registry Number
5	Cofactor
2	KM Value [mM]
5	Metals/Ions
6	Natural Substrates/ Products (Substrates)
181	Organism
5	pH Optimum
5	pH Range
5	Purification (Commentary)
1	Reaction
1	Reaction Type
6	Reference
2	Source Tissue
1	Storage Stability
24	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 4.3.2.4 - purine imidazole-ring cyclase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

6 entries

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

6 entries

additional information

?

-

12 entries

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

Chlorocebus aethiops

-

imidazole-ring-opened guanine

648690

-

-

?

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

Cricetulus griseus

-

imidazole-ring-opened guanine

648690

-

-

?

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

Escherichia coli

-

imidazole-ring-opened guanine

648690

-

-

?

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

Escherichia coli B / ATCC 11303

-

imidazole-ring-opened guanine

648690

-

-

?

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

Lacticaseibacillus casei

-

imidazole-ring-opened guanine

648690

-

-

?

DNA 2,6-diamino-4-oxo-5-formamidopyrimidine

DNA guanine + H2O

Proteus mirabilis

-

imidazole-ring-opened guanine

648690

-

-

?

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

Chlorocebus aethiops

-

imidazole-ring-opened adenine, ring closure to restore C8 to N9 linkage

648690

-

648690

?

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

Cricetulus griseus

-

imidazole-ring-opened adenine, ring closure to restore C8 to N9 linkage

648690

-

648690

?

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

Escherichia coli

-

imidazole-ring-opened adenine, ring closure to restore C8 to N9 linkage

648690

-

648690

?

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

Escherichia coli B / ATCC 11303

-

imidazole-ring-opened adenine, ring closure to restore C8 to N9 linkage

648690

-

648690

?

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

Lacticaseibacillus casei

-

imidazole-ring-opened adenine, ring closure to restore C8 to N9 linkage

648690

-

648690

?

DNA 4,6-diamino-5-formamidopyrimidine

DNA adenine + H2O

Proteus mirabilis

-

imidazole-ring-opened adenine, ring closure to restore C8 to N9 linkage

648690

-

648690

?

additional information

?

-

Chlorocebus aethiops

-

not: opened imidazole ring of 7-methylguanine-derived formamidopyrimidine in DNA

648690

-

-

?

additional information

?

-

Chlorocebus aethiops

-

repair of formamidopyrimidine lesions in DNA, reclosure of the imidazole ring to restore the C8 to N9 linkage previously cleaved by ionizing radiation

648690

-

-

?

additional information

?

-

Cricetulus griseus

-

not: opened imidazole ring of 7-methylguanine-derived formamidopyrimidine in DNA

648690

-

-

?

additional information

?

-

Cricetulus griseus

-

repair of formamidopyrimidine lesions in DNA, reclosure of the imidazole ring to restore the C8 to N9 linkage previously cleaved by ionizing radiation

648690

-

-

?

additional information

?

-

Escherichia coli

-

not: opened imidazole ring of 7-methylguanine-derived formamidopyrimidine in DNA

648690

-

-

?

additional information

?

-

Escherichia coli

-

repair of formamidopyrimidine lesions in DNA, reclosure of the imidazole ring to restore the C8 to N9 linkage previously cleaved by ionizing radiation

648690

-

-

?

additional information

?

-

Escherichia coli B / ATCC 11303

-

not: opened imidazole ring of 7-methylguanine-derived formamidopyrimidine in DNA

648690

-

-

?

additional information

?

-

Escherichia coli B / ATCC 11303

-

repair of formamidopyrimidine lesions in DNA, reclosure of the imidazole ring to restore the C8 to N9 linkage previously cleaved by ionizing radiation

648690

-

-

?

additional information

?

-

Lacticaseibacillus casei

-

not: opened imidazole ring of 7-methylguanine-derived formamidopyrimidine in DNA

648690

-

-

?

additional information

?

-

Lacticaseibacillus casei

-

repair of formamidopyrimidine lesions in DNA, reclosure of the imidazole ring to restore the C8 to N9 linkage previously cleaved by ionizing radiation

648690

-

-

?

additional information

?

-

Proteus mirabilis

-

not: opened imidazole ring of 7-methylguanine-derived formamidopyrimidine in DNA

648690

-

-

?

additional information

?

-

Proteus mirabilis

-

repair of formamidopyrimidine lesions in DNA, reclosure of the imidazole ring to restore the C8 to N9 linkage previously cleaved by ionizing radiation

648690

-

-

?