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4.3.1.9: glucosaminate ammonia-lyase

This is an abbreviated version!
For detailed information about glucosaminate ammonia-lyase, go to the full flat file.

Reaction

(2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate
=
(4S,5R)-4,5,6-trihydroxy-2-iminohexanoate

Synonyms

ammonia-lyase, glucosaminate, D-glucosaminate dehydrogenase, D-glucosaminic acid dehydrase, EC 4.2.1.26, EC 4.3.1.21, GADH

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.9 glucosaminate ammonia-lyase

Systematic Name

Systematic Name on EC 4.3.1.9 - glucosaminate ammonia-lyase

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SYSTEMATIC NAME
IUBMB Comments
D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)
Contains pyridoxal phosphate. The enzyme releases an unstable enamine product that tautomerizes to an imine form, which undergoes spontaneous hydrolytic deamination to form the final product.