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4.3.1.24: phenylalanine ammonia-lyase

This is an abbreviated version!
For detailed information about phenylalanine ammonia-lyase, go to the full flat file.

Word Map on EC 4.3.1.24

Reaction

L-phenylalanine
=
trans-cinnamate
+
NH3

Synonyms

AtPAL 1, AtPAL 2, AtPAL 3, AtPAL 4, AtPAL-1, AtPAL-2, AtPAL-3, AtPAL-4, AtPAL2, AvPAL, DcPAL1, EC 4.3.1.5, EncP, L-phenylalanine ammonia-lyase, L-phenylalanine-ammonia lyase, LrPAL3, LsPAL1, More, PAL, PAL-CLEA, PAL1, PAL2, PAL3, PAL3a, PAL3b, PAL4, PAL5, PAL6, PALrs1, PcPAL1, Phe ammonia-lyase, phenylalanine ammonia lyase, phenylalanine ammonia-lyase, phenylalanine ammonia-lyase 1, phenylalanine ammonia-lyase 2, phenylalanine ammonia-lyase 3, phenylalanine ammonia-lyase 4, RgPAL, RxPAL, Sb04g026520, SsPAL1, TcPAL, ZmPAL2

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.24 phenylalanine ammonia-lyase

pH Range

pH Range on EC 4.3.1.24 - phenylalanine ammonia-lyase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 12
-
pH-dependent activity profile
6 - 10
-
pH 6.0: about 60% of maximal activity (immobilized enzyme), about 40% of maximal activity (soluble enzyme), pH 10.0: about 90% of maximal activity (immobilized enzyme), about 80% of maximal activity (soluble enzyme)
6.8 - 9.2
-
pH 6.5: 50% of maximal activity, pH 8.8-9.2: optimum
7 - 10
7 - 10.5
7 - 11
7.3 - 8.5
-
the enzyme maintains 70% of its highest activity (at pH 8.5) when pH decreases to 7.3-7.4
7.5 - 10
pH 7.5: about 40% of maximal activity, pH 10.0: about 75% of maximal activity
7.5 - 8.5
highest activity of wild-type and mutant enzyme
7.5 - 9
-
pH 7.5: about 70% of maximal activity, pH 9.0: about 70% of maximal activity
7.8 - 9
Coleus scutellarioides
pH 7.8: about 75% of maximal activity, pH 9.0: about 70% of maximal activity
8 - 11
-
pH 8: about 50% of maximal activity, pH 11: about 80% of maximal activity, enzyme form PAL-I
8 - 9
-
optimal activity