4.3.1.17: L-serine ammonia-lyase

This is an abbreviated version!
For detailed information about L-serine ammonia-lyase, go to the full flat file.

Word Map on EC 4.3.1.17

4.3.1.17

aminotransferase

pyridoxal

deamination

glucagon

gluconeogenesis

gluconeogenic

hydroxymethyltransferase

l-isoleucine

d-serine

plp-dependent

peptostreptococcus

deaminases

2-oxobutyrate

asaccharolyticus

analysis

medicine

Reaction

Synonyms

bsLSD type 1, cSDH, Dehydratase, L-serine, EC 4.2.1.13, GSU0486, HSDH, L-Hydroxy amino acid dehydratase, L-SD, L-SD1, L-SD2, L-serine ammonia-lyase, L-Serine deaminase, L-serine deaminase 2, L-serine dehydratase, L-serine dehydratase 1, L-serine dehydratase 2, L-threonine deaminase, L-threonine dehydratase, lpLSD, lpLSD type 2, More, MSMEG_3532, PH0054, SD, SdaA, SdaB, SDH, SDH-like-1, SDH1, SDH2, SdhA, SerDH, Serine deaminase, Serine dehydratase, serine dehydratase like-1, tdcB, TdcG

ECTree

4 Lyases

4.3 Carbon-nitrogen lyases

4.3.1 Ammonia-lyases

4.3.1.17 L-serine ammonia-lyase

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Results	in table
4	Activating Compound
35908	AA Sequence
3	Application
1	CAS Registry Number
14	Cloned(Commentary)
33	Cofactor
8	Crystallization (Commentary)
89	Disease/ Diagnostics
2	General Information
5	General Stability
1	IC50 Value
72	Inhibitors
24	kcat/KM [mM/s]
7	Ki Value [mM]
83	KM Value [mM]
3	Localization
32	Metals/Ions
66	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
90	Organism
6	Oxidation Stability
8	Pathway
49	PDB ID
24	pH Optimum
5	pH Range
6	pH Stability
1	pI Value
43	Protein Variants
37	Purification (Commentary)
7	Reaction
5	Reaction Type
84	Reference
27	Source Tissue
32	Specific Activity [micromol/min/mg]
10	Storage Stability
139	Substrates and Products (Substrate)
30	Subunits
90	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
1	Temperature Range [°C]
13	Temperature Stability [°C]
42	Turnover Number [1/s]

Oxidation Stability

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Oxidation Stability on EC 4.3.1.17 - L-serine ammonia-lyase

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complete loss of activity in crude extracts after exposure to air for 1 h

Paracoccus seriniphilus

650851

inactivated upon exposure to air, reactivated by Fe2+ under aerobic conditions

2 entries

purified SdaA is inactivated with a half-life of approx. 1.5 h upon exposure to air, inactivated SdaA can be reactivated to approx. 60% of its activity under strict anaerobic conditiones with Fe2+ and dithiothreitol

Campylobacter jejuni

651494

rapid loss of activity upon exposure to air, reactivation by Fe2+

2 entries