4.3.1.10: serine-sulfate ammonia-lyase

This is an abbreviated version!
For detailed information about serine-sulfate ammonia-lyase, go to the full flat file.

Reaction

Synonyms

(L-SOS) lyase, ammonia-lyase, serine sulfate

ECTree

     4 Lyases

         4.3 Carbon-nitrogen lyases

             4.3.1 Ammonia-lyases

                4.3.1.10 serine-sulfate ammonia-lyase

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Results	in table
1	CAS Registry Number
1	General Stability
56	Inhibitors
21	KM Value [mM]
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
20	Organism
1	Oxidation Stability
3	pH Optimum
1	pH Range
1	pH Stability
4	Purification (Commentary)
2	Reaction
1	Reaction Type
20	Reference
18	Source Tissue
6	Specific Activity [micromol/min/mg]
4	Storage Stability
83	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 4.3.1.10 - serine-sulfate ammonia-lyase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3-chloro-L-alanine methyl ester

?

3 entries

3-cyano-L-alanine

?

Pseudomonas sp.

-

-

6035

-

-

?

beta-chloroalanine

?

2 entries

beta-ureido-alpha-aminopropionic acid

?

Pseudomonas sp.

-

-

6035

-

-

?

D-cystathionine

?

Pseudomonas sp.

-

-

6035

-

-

?

D-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

D-cystine

?

Pseudomonas sp.

-

-

6035

-

-

?

D-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

D-serine-O-sulfate

pyruvate + NH3 + SO42-

3 entries

DL-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

DL-lanthionine

?

Pseudomonas sp.

-

-

6035

-

-

?

L-cystathionine + H2O

?

Pseudomonas sp.

-

-

6035

-

-

?

L-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

L-cystine

?

Pseudomonas sp.

-

-

6035

-

-

?

L-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

L-serine O-sulfate

?

10 entries

L-serine O-sulfate

pyruvate + NH3 + sulfate

19 entries

L-seryl-glycine O-sulfate

?

2 entries

L-seryl-L-alanine O-sulfate

?

2 entries

L-seryl-L-leucine O-sulfate

?

2 entries

L-seryl-L-phenylalanine O-sulfate

?

2 entries

L-seryl-L-valine O-sulfate

?

2 entries

L-threonine O-sulfate

2-oxobutanoate + NH3 + SO42-

5 entries

O-acetyl-L-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

O-benzyl DL-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

O-benzyl-L-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

O-diazoacetyl-L-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

O-methyl DL-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

O-succinyl-L-serine

?

Pseudomonas sp.

-

-

6035

-

-

?

S-benzyl-L-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

S-carbamoyl-L-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

S-ethyl-L-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

S-methyl L-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

S-methyl-L-cysteine

?

Pseudomonas sp.

-

growth pattern is similar to that observed with L-serine O-sulfate

6035

-

-

?

S-sulfo-L-cysteine

?

Pseudomonas sp.

-

-

6035

-

-

?

additional information

?

-

6 entries

3-chloro-L-alanine methyl ester

?

Pseudomonas sp.

-

3-chloro-L-alanine

6035

-

-

?

3-chloro-L-alanine methyl ester

?

Pseudomonas sp. FR

-

3-chloro-L-alanine

6035

-

-

?

3-chloro-L-alanine methyl ester

?

Sus scrofa

-

-

6032

-

-

?

beta-chloroalanine

?

Rattus norvegicus

-

-

6034

-

-

?

beta-chloroalanine

?

Rattus norvegicus

-

beta-chloro-L-alanine

6039

-

-

?

D-serine-O-sulfate

pyruvate + NH3 + SO42-

Pseudomonas sp.

-

-

6035

-

-

?

D-serine-O-sulfate

pyruvate + NH3 + SO42-

Rattus norvegicus

-

-

6039

-

-

?

D-serine-O-sulfate

pyruvate + NH3 + SO42-

Rattus norvegicus

-

activity: 1/40 that towards L-isomer

6034

-

-

?

L-serine O-sulfate

?

Allium cepa

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Allium sativum

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Brassica rapa subsp. oleifera

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Citrullus lanatus subsp. vulgaris

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Fagopyrum esculentum

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Leucaena leucocephala

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Mimosa pudica

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Pisum sativum

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Raphanus sativus

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

?

Vigna radiata var. radiata

-

biosynthesis of cysteine derivates

6031

-

-

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Allium cepa

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Allium sativum

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Brassica rapa subsp. oleifera

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Citrullus lanatus subsp. vulgaris

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Fagopyrum esculentum

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Leucaena leucocephala

-

optimum concentration 188 mM

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Leucaena leucocephala

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Mimosa pudica

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Pisum sativum

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Pseudomonas sp.

-

-

6035

-

6035

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Pseudomonas sp. FR

-

-

6035

-

6035

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Raphanus sativus

-

quite specific

6031

-

6031

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Rattus norvegicus

-

-

6034

-

6034

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Rattus norvegicus

-

-

6036

-

-

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Rattus norvegicus

-

-

6039

-

6039

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Sus scrofa

-

-

6032

-

6032

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Sus scrofa

-

-

6033, 6037

-

-

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Sus scrofa

-

optimum activity at a concentration of 0.05 M

6038

-

-

?

L-serine O-sulfate

pyruvate + NH3 + sulfate

Vigna radiata var. radiata

-

quite specific

6031

-

6031

?

L-seryl-glycine O-sulfate

?

Rattus norvegicus

-

-

6039

-

-

?

L-seryl-glycine O-sulfate

?

Rattus norvegicus

-

not very efficient substrate

6034

-

-

?

L-seryl-L-alanine O-sulfate

?

Rattus norvegicus

-

-

6039

-

-

?

L-seryl-L-alanine O-sulfate

?

Rattus norvegicus

-

not very efficient substrate

6034

-

-

?

L-seryl-L-leucine O-sulfate

?

Rattus norvegicus

-

-

6039

-

-

?

L-seryl-L-leucine O-sulfate

?

Rattus norvegicus

-

not very efficient substrate

6034

-

-

?

L-seryl-L-phenylalanine O-sulfate

?

Rattus norvegicus

-

-

6039

-

-

?

L-seryl-L-phenylalanine O-sulfate

?

Rattus norvegicus

-

not very efficient substrate

6034

-

-

?

L-seryl-L-valine O-sulfate

?

Rattus norvegicus

-

-

6039

-

-

?

L-seryl-L-valine O-sulfate

?

Rattus norvegicus

-

not very efficient substrate

6034

-

-

?

L-threonine O-sulfate

2-oxobutanoate + NH3 + SO42-

Leucaena leucocephala

-

activity: 1/30 that towards L-serine O-sulfate

6031

-

-

?

L-threonine O-sulfate

2-oxobutanoate + NH3 + SO42-

Pseudomonas sp.

-

-

6035

-

-

?

L-threonine O-sulfate

2-oxobutanoate + NH3 + SO42-

Pseudomonas sp. FR

-

-

6035

-

-

?

L-threonine O-sulfate

2-oxobutanoate + NH3 + SO42-

Rattus norvegicus

-

-

6039

-

-

?

L-threonine O-sulfate

2-oxobutanoate + NH3 + SO42-

Rattus norvegicus

-

weak activity

6034

-

-

?

additional information

?

-

Pseudomonas sp.

-

multi-substrate activity of the enzymes A and B with the enzyme A having a preferential activity for L-isomers and enzyme B for D-isomers

6035

-

-

?

additional information

?

-

Pseudomonas sp.

-

Pseudomonas FR posses two distinct L-serine O-sulfate degrading enzymes (A and B)

6035

-

-

?

additional information

?

-

Pseudomonas sp. FR

-

multi-substrate activity of the enzymes A and B with the enzyme A having a preferential activity for L-isomers and enzyme B for D-isomers

6035

-

-

?

additional information

?

-

Pseudomonas sp. FR

-

Pseudomonas FR posses two distinct L-serine O-sulfate degrading enzymes (A and B)

6035

-

-

?

additional information

?

-

Rattus norvegicus

-

factors affecting the leavels of th L-serine O-sulfate-degrading system

6036

-

-

?

additional information

?

-

Sus scrofa

-

aminoacrylate is an intermediate in the enzyme-catalysed degradation of L-serine O-sulfate

6037

-

-

?