4.3.1.1: aspartate ammonia-lyase

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For detailed information about aspartate ammonia-lyase, go to the full flat file.

Reaction

Synonyms

ammonia-lyase, aspartate, ASPA, aspartase, aspartate ammonia lyase, aspartate ammonia-lyase, aspartate:ammonia lyase, aspB, Cj0087, fumaric aminase, L-aspartase, L-aspartate ammonia lyase, L-aspartate ammonia-lyase, maspase 1, maspase 2, maspase 3

ECTree

4 Lyases

4.3 Carbon-nitrogen lyases

4.3.1 Ammonia-lyases

4.3.1.1 aspartate ammonia-lyase

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Results	in table
23	Activating Compound
11980	AA Sequence
15	Application
1	CAS Registry Number
18	Cloned(Commentary)
7	Crystallization (Commentary)
1	Expression
3	General Information
7	General Stability
88	Inhibitors
20	kcat/KM [mM/s]
17	Ki Value [mM]
83	KM Value [mM]
49	Metals/Ions
40	Molecular Weight [Da]
31	Natural Substrates/ Products (Substrates)
135	Organism
1	Oxidation Stability
8	Pathway
42	PDB ID
58	pH Optimum
9	pH Range
5	pH Stability
59	Protein Variants
22	Purification (Commentary)
17	Reaction
13	Reaction Type
110	Reference
10	Renatured (Commentary)
11	Source Tissue
84	Specific Activity [micromol/min/mg]
13	Storage Stability
189	Substrates and Products (Substrate)
45	Subunits
56	Synonyms
1	Systematic Name
20	Temperature Optimum [°C]
8	Temperature Range [°C]
22	Temperature Stability [°C]
50	Turnover Number [1/s]

Oxidation Stability

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Oxidation Stability on EC 4.3.1.1 - aspartate ammonia-lyase

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over 24 h of microaerobic batch growth, the AspA specific enzyme activity increases 10fold and the relative abundance of the protein increases over 13fold. After transferring initially microaerobic cultures to oxygenlimiting conditions in the absence of an added electron acceptor, there is an immediate cessation of growth but an approximately 3fold rise in AspA specific activity up to 24 h correlated with a smaller increase in the abundance of the protein.

Campylobacter jejuni

Q0PC50

694233