4.3.1.1: aspartate ammonia-lyase
This is an abbreviated version!
For detailed information about aspartate ammonia-lyase, go to the full flat file.
Reaction
Synonyms
ammonia-lyase, aspartate, ASPA, aspartase, aspartate ammonia lyase, aspartate ammonia-lyase, aspartate:ammonia lyase, aspB, Cj0087, fumaric aminase, L-aspartase, L-aspartate ammonia lyase, L-aspartate ammonia-lyase, maspase 1, maspase 2, maspase 3
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Natural Substrates Products
Natural Substrates Products on EC 4.3.1.1 - aspartate ammonia-lyase
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REACTION DIAGRAM
L-aspartate
important enzyme in production of L-aspartate
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r
fumarate + NH3
L-aspartate
important enzyme in production of L-aspartate
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r
fumarate + NH3
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key role in nitrogen metabolism by catalyzing the reversible elimination of NH3 from l-aspartate
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r
L-aspartate
fumarate + NH3
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fumarate is a component of the tricarboxylic acid (TCA) cycle
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L-aspartate
fumarate + NH3
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fumarate is a component of the tricarboxylic acid (TCA) cycle
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important role in the bacterial nitrogen metabolism
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Bacillus sp. (in: Bacteria) YM55-1
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important role in the bacterial nitrogen metabolism
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AspA is one of the most specific enzymes known, no other substrates can replace L-aspartic acid in the deamination reaction
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aspartate enhances oxygen-limited strain growth via fumarate respiration in an aspA-dependent manner
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aspartate enhances oxygen-limited strain growth via fumarate respiration in an aspA-dependent manner
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both wild-type and AspA mutant Campylobacter jejuni strains show similar fumarate-dependent growth
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both wild-type and AspA mutant Campylobacter jejuni strains show similar fumarate-dependent growth
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L-aspartate ammonia-lyase and fumarate hydratase share extensive sequence homology
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L-aspartate ammonia-lyase and fumarate hydratase share extensive sequence homology
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enzyme synthesis is subject to catabolite repression by glucose and is suppressed under aerobic conditions
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enzyme is essential for the catabolism of the glutamate
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aspartase, fumarase and argininosuccinase are structurally-related enzymes
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one of the enzymes of the aspartate metabolism in lactic acid bacteria
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Ligilactobacillus murinus CNRZ 313
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one of the enzymes of the aspartate metabolism in lactic acid bacteria
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key enzyme involved in the metabolism of aspartate
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additional information
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L-aspartate ammonia-lyase and fumarate hydratase share extensive sequence homology
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