4.2.99.21: isochorismate lyase

This is an abbreviated version!
For detailed information about isochorismate lyase, go to the full flat file.

Word Map on EC 4.2.99.21

4.2.99.21

siderophore

pericyclic

chorismate-utilizing

prephenate

2,3-dihydroxybenzoate

anthranilate

mg2+-dependent

enterobactin

drug development

agriculture

biotechnology

synthesis

Reaction

Synonyms

pyochelin biosynthetic protein PchB, IPL, Irp9, isochorismate pyruvate lyase, isochorismate-pyruvate lyase, MbtI, PchA, PchB, PRXR1, salicylate biosynthesis protein pchB, salicylate synthase

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.99 Other carbon-oxygen lyases

4.2.99.21 isochorismate lyase

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Results	in table
76	AA Sequence
5	Application
1	CAS Registry Number
9	Cloned(Commentary)
1	Cofactor
9	Crystallization (Commentary)
1	Expression
23	General Information
84	Inhibitors
32	kcat/KM [mM/s]
16	Ki Value [mM]
32	KM Value [mM]
8	Metals/Ions
9	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
41	Organism
3	Pathway
12	PDB ID
3	pH Optimum
3	pH Range
1	pI Value
38	Protein Variants
3	Purification (Commentary)
14	Reaction
37	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
47	Substrates and Products (Substrate)
7	Subunits
44	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
34	Turnover Number [1/s]

KI Value

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KI Value on EC 4.2.99.21 - isochorismate lyase

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0.16

(4R,5R)-5-[(1-carboxyethenyl)oxy]-4-hydroxycyclohex-1-ene-1-carboxylic acid

2 entries

0.013

(E)-3-(1-carboxyprop-1-enyloxy)-2-hydroxybenzoic acid

Mycobacterium tuberculosis

pH 8.0, 25°C

708123

0.024

2-amino-3-(1-carboxyethoxy)benzoic acid

Yersinia enterocolitica

pH not specified in the publication, temperature not specified in the publication

710180

0.021

3-(1-carboxy-2-phenylvinyloxy)-2-hydroxybenzoic acid

Mycobacterium tuberculosis

pH 8.0, 25°C

708123

0.014

3-(1-carboxy-3-methylbut-1-enyloxy)-2-hydroxybenzoic acid

Mycobacterium tuberculosis

pH 8.0, 25°C

708123

0.012

3-(1-carboxybut-1-enyloxy)-2-hydroxybenzoic acid

Mycobacterium tuberculosis

pH 8.0, 25°C

708123

0.019

3-(1-carboxyethoxy)-2-hydroxybenzoic acid

Yersinia enterocolitica

pH not specified in the publication, temperature not specified in the publication

710180

1.4

3-(1-carboxyethoxy)-4,5-dihydroxybenzoic acid

Mycobacterium tuberculosis

P9WFX1

pH and temperature not specified in the publication

747617

1.7

3-[(1-carboxyethenyl)oxy]-4,5-dihydroxybenzoic acid

Mycobacterium tuberculosis

P9WFX1

pH and temperature not specified in the publication

747617

3-[(2-carboxyprop-2-en-1-yl)oxy]-4,5-dihydroxybenzoic acid

Mycobacterium tuberculosis

P9WFX1

pH and temperature not specified in the publication

747617

0.0001

4,4'-sulfonylbis(2,6-dinitrophenol)

Pseudomonas aeruginosa

Q51507

pH and temperature not specified in the publication

747617

0.00087

4,6-dinitro-2-oxo-1,3-benzoxathiol-5-yl methyl carbonate

Pseudomonas aeruginosa

Q51507

pH and temperature not specified in the publication

747617

0.025

4,6-dinitro-2-oxo-2H-1,3-benzoxathiol-5-yl methyl carbonate

Yersinia enterocolitica

pH and temperature not specified in the publication

747617

0.043

4-amino-3-(1-carboxyethoxy)benzoic acid

Yersinia enterocolitica

pH not specified in the publication, temperature not specified in the publication

710180

0.0001

5-[(2-carboxyphenyl)sulfamoyl]-2-hydroxybenzoic acid

Pseudomonas aeruginosa

Q51507

pH and temperature not specified in the publication

747617