Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.2.3.9: aristolochene synthase

This is an abbreviated version!
For detailed information about aristolochene synthase, go to the full flat file.

Word Map on EC 4.2.3.9

Reaction

(2E,6E)-farnesyl diphosphate
=
aristolochene
 +
diphosphate

Synonyms

5-epi-aristolochene synthase, Ari1, aristolochene synthase, AS, ATAS, cyclase, farnesyl pyrophosphate, EAS, EC 2.5.1.40, EC 4.1.99.7, farnesylpyrophosphate cyclase, FPP-carbocyclase, sesquiterpene cyclase, synthase, aristolochene, TEAS

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.9 aristolochene synthase

Inhibitors

Inhibitors on EC 4.2.3.9 - aristolochene synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(4aS,7S)-1,4a-dimethyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolinium iodide
inhibitor mimics transition state associated with the cyclization of (-)-germacrene A to eudesmane cation, competitive
(4aS,7S)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolinium chloride
inhibitor mimics transition state associated with the cyclization of (-)-germacrene A to eudesmane cation, competitive
12,13-difluoro-farnesyl diphosphate
-
-
12,13-difluorofarnesyl diphosphate
3-phenylfarnesyl diphosphate
-
4-aza-eudesm-11-ene
-
transition state analogue, competitive
anilinogeranyl diphosphate
potent noncompetitive inhibitor
E-11-phenylfarnesyl diphosphate
-
farnesyl thiodiphosphate
-
-
Z-11-phenylfarnesyl diphosphate
-
additional information
-
no effect: phosphate up to concentrations of 5.0 mM
-