4.2.3.5: chorismate synthase

This is an abbreviated version!
For detailed information about chorismate synthase, go to the full flat file.

Word Map on EC 4.2.3.5

4.2.3.5

flavin

dahps

7-phosphate

3-deoxy-d-arabino-heptulosonate

sempervirens

dehydroquinate

corydalis

drug development

Reaction

Synonyms

5-enolpyruvylshikimate-3-phosphate phospholyase, 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate lyase, ARO2, aroC, aroF, chorismate synthase, chorismate synthetase, CS, CS1, CS2, EC 4.6.1.4, MtCS, VEG216, Vegetative protein 216, Vlaro2

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.3 Acting on phosphates

4.2.3.5 chorismate synthase

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Results	in table
1	Activating Compound
43157	AA Sequence
1	Application
1	CAS Registry Number
23	Cloned(Commentary)
46	Cofactor
9	Crystallization (Commentary)
1	Expression
2	General Information
3	General Stability
1	IC50 Value
42	Inhibitors
35	Ki Value [mM]
17	KM Value [mM]
2	Localization
1	Metals/Ions
35	Molecular Weight [Da]
44	Natural Substrates/ Products (Substrates)
75	Organism
6	Pathway
42	PDB ID
9	pH Optimum
6	pI Value
3	Posttranslational Modification
9	Protein Variants
17	Purification (Commentary)
9	Reaction
8	Reaction Type
74	Reference
7	Source Tissue
19	Specific Activity [micromol/min/mg]
7	Storage Stability
87	Substrates and Products (Substrate)
35	Subunits
37	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 4.2.3.5 - chorismate synthase

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5-enolpyruvylshikimate 3-phosphate

chorismate + phosphate

13 entries

5-enolpyruvylshikimate-3-phosphate

chorismate + phosphate

Streptococcus pneumoniae

679365

5-O-(1-carboxyvinyl)-3-phosphoshikimate

chorismate + phosphate

6 entries

O5-(1-carboxyvinyl)-3-phosphoshikimate

4 entries

O5-(1-carboxyvinyl)-3-phosphoshikimate

chorismate + phosphate

17 entries

additional information

Neurospora crassa

the dissociation constant for the S127A mutant protein is similar to that of the wild-type enzyme, whereas the replacement of S16 with alanine results in a slight increase of the dissociation constant

692285