4.2.3.5: chorismate synthase

This is an abbreviated version!
For detailed information about chorismate synthase, go to the full flat file.

Reaction

Synonyms

5-enolpyruvylshikimate-3-phosphate phospholyase, 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate lyase, ARO2, aroC, aroF, chorismate synthase, chorismate synthetase, CS, CS1, CS2, EC 4.6.1.4, MtCS, VEG216, Vegetative protein 216, Vlaro2

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.3 Acting on phosphates

                4.2.3.5 chorismate synthase

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Results	in table
1	Activating Compound
43157	AA Sequence
1	Application
1	CAS Registry Number
23	Cloned(Commentary)
46	Cofactor
9	Crystallization (Commentary)
1	Expression
2	General Information
3	General Stability
1	IC50 Value
42	Inhibitors
35	Ki Value [mM]
17	KM Value [mM]
2	Localization
1	Metals/Ions
35	Molecular Weight [Da]
44	Natural Substrates/ Products (Substrates)
75	Organism
6	Pathway
42	PDB ID
9	pH Optimum
6	pI Value
3	Posttranslational Modification
9	Protein Variants
17	Purification (Commentary)
9	Reaction
8	Reaction Type
74	Reference
7	Source Tissue
19	Specific Activity [micromol/min/mg]
7	Storage Stability
87	Substrates and Products (Substrate)
35	Subunits
37	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 4.2.3.5 - chorismate synthase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.25

(6R)-6-fluoro-5-enoylpyruvylshikimate 3-phosphate

Escherichia coli

-

IC50 is 0.0005 mM when the enzyme is preincubated with the inhibitor, the IC50 is 0.25 mM when the enzyme is not preincubated with the inhibitor, inhibition is not absolutely irreversible

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