4.2.3.5: chorismate synthase
This is an abbreviated version!
For detailed information about chorismate synthase, go to the full flat file.
Word Map on EC 4.2.3.5
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4.2.3.5
-
flavin
-
dahps
-
7-phosphate
-
3-deoxy-d-arabino-heptulosonate
-
sempervirens
-
dehydroquinate
-
corydalis
-
drug development
- 4.2.3.5
- flavin
- dahps
- 7-phosphate
-
3-deoxy-d-arabino-heptulosonate
- sempervirens
- dehydroquinate
- corydalis
- drug development
Reaction
Synonyms
5-enolpyruvylshikimate-3-phosphate phospholyase, 5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate lyase, ARO2, aroC, aroF, chorismate synthase, chorismate synthetase, CS, CS1, CS2, EC 4.6.1.4, MtCS, VEG216, Vegetative protein 216, Vlaro2
ECTree
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Cofactor
Cofactor on EC 4.2.3.5 - chorismate synthase
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FMN
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reduced, the S16A/S127A double-mutant protein showy slightly weaker binding of the cofactor
FMNH2
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absolute requirement for FMNH2, which is not consumed during the reaction
FMNH2
required. The unique FMN-binding site is formed largely by a single subunit, with a small contribution from a neighboring subunit. The isoalloxazine ring of the bound FMN is significantly non-planar