4.2.3.4: 3-dehydroquinate synthase
This is an abbreviated version!
For detailed information about 3-dehydroquinate synthase, go to the full flat file.
Word Map on EC 4.2.3.4
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4.2.3.4
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shikimate
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dahp
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3-deoxy-d-arabino-heptulosonate
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chorismate
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pentafunctional
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3-phosphoshikimate
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3-dehydroquinase
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1-carboxyvinyltransferase
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drug development
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medicine
- 4.2.3.4
- shikimate
- dahp
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3-deoxy-d-arabino-heptulosonate
- chorismate
-
pentafunctional
- 3-phosphoshikimate
- 3-dehydroquinase
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1-carboxyvinyltransferase
- drug development
- medicine
Reaction
Synonyms
3-dehydroquinate synthase, 3-dehydroquinate synthetase, 3-dehydroquinic acid synthetase, 5-dehydroquinate synthase, 5-dehydroquinic acid synthetase, aroB, dehydroquinate synthase, dehydroquinate synthetase, DHQ synthase, DHQS, EC 4.6.1.3, hpDHQS, synthase, 5-dehydroquinate, Xoo1243
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Natural Substrates Products
Natural Substrates Products on EC 4.2.3.4 - 3-dehydroquinate synthase
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REACTION DIAGRAM
3-deoxy-D-arabino-heptulosonate 7-phosphate
3-dehydroquinate + phosphate
second key step in the shikimate pathway which is crucial for the aromatic amino acid metabolism in bacteria, fungi, and plants, but not in mammals
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3-deoxy-D-arabinoheptulosonate 7-phosphate
3-dehydroquinate + phosphate
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shikimate pathway is present in all organisms except mammals
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additional information
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enzyme plays an essential role in the synthesis of aromatic compounds in the shikimate pathway
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3-dehydroquinate + phosphate
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ir
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
3-dehydroquinate + phosphate
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?
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
3-dehydroquinate + phosphate
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ir
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
3-dehydroquinate + phosphate
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-
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ir
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
3-dehydroquinate + phosphate
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?
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
3-dehydroquinate + phosphate
the enzyme catalyses the second step of the shikimate pathway to aromatic compounds
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