4.2.3.32: levopimaradiene synthase

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For detailed information about levopimaradiene synthase, go to the full flat file.

Word Map on EC 4.2.3.32

4.2.3.32

diterpene

spruce

picea

conifer

terpenoids

norway

jasmonate

geranylgeranyl

biloba

ginkgo

diterpenoid

oleoresin

traumatic

ginkgolide

cambial

sitchensis

gymnosperm

grandis

synthesis

taeda

linalool

sitka

limonene

Reaction

Synonyms

abietadiene synthase, levopimaradiene/abietadiene synthase, LP synthase, LPS, More, PaLAS, TPS-LAS

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.3 Acting on phosphates

4.2.3.32 levopimaradiene synthase

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Results	in table
1	Activating Compound
8	AA Sequence
2	Application
1	CAS Registry Number
5	Cloned(Commentary)
1	Crystallization (Commentary)
2	General Information
5	Localization
3	Metals/Ions
1	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
9	Organism
3	Pathway
1	pH Optimum
1	Posttranslational Modification
30	Protein Variants
1	Reaction
2	Reaction Type
9	Reference
5	Source Tissue
9	Substrates and Products (Substrate)
1	Subunits
9	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 4.2.3.32 - levopimaradiene synthase

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(+)-copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]

In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists [1]. Levopimaradiene is widely distributed in higher plants. In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene [2].