4.2.3.23: germacrene-A synthase
This is an abbreviated version!
For detailed information about germacrene-A synthase, go to the full flat file.
Word Map on EC 4.2.3.23
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4.2.3.23
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sesquiterpene
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terpene
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lactones
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farnesyl
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+-germacrene
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asteraceae
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chicory
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cichorium
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annua
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costunolide
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cynaropicrin
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feverfew
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cynara
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cardunculus
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intybus
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parthenolide
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amorpha-4,11-diene
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parthenium
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tanacetum
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analysis
- 4.2.3.23
-
sesquiterpene
-
terpene
- lactones
-
farnesyl
-
+-germacrene
- asteraceae
- chicory
-
cichorium
- annua
- costunolide
- cynaropicrin
- feverfew
-
cynara
- cardunculus
- intybus
- parthenolide
- amorpha-4,11-diene
- parthenium
-
tanacetum
- analysis
Reaction
Synonyms
(+)-(10R)-germacrene A synthase, (+)-germacrene A synthase, FENS, GAS, GAS1, GAS2, GASlo, GASsh, germacrene A synthase, germacrene A synthase 1, germacrene A synthase 2, guaiadiene synthase, NS1, Sc1, sesquiterpene cyclase, sesquiterpene synthase
ECTree
4.2.3.23 germacrene-A synthaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 4.2.3.23 - germacrene-A synthase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(2E,6E)-farnesyl diphosphate
(+)-(R)-germacrene A + beta-elemene + beta-selinene + alpha-selinene + diphosphate
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-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-(R)-germacrene A + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-(R)-germacrene A + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-(R)-germacrene A + diphosphate
-
-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
-
-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
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-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
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the product germacerene A is released after reaction to be further processing by oxidations and/or glucosylations and cyclization by a germacrane cyclase
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-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
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-
-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
-
-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
-
-
-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
-
-
-
-
?
2-trans,6-trans-farnesyl diphosphate
(+)-(10R)-germacrene A + diphosphate
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98% of total product is (+)-(10R)-germacrene A, 2% is alpha-humulene in feeding experiments in vivo
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?
additional information
?
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(+)-germacrene A synthesis is a step in isoprenoid biosynthesis, overview
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-
?
additional information
?
-
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(+)-germacrene A synthesis is a step in isoprenoid biosynthesis, overview
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-
?
additional information
?
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-
(+)-germacrene A synthesis is the committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
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-
?
additional information
?
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(+)-germacrene A synthesis is the committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
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-
?
additional information
?
-
(+)-germacrene A synthesis is the committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
-
-
?
additional information
?
-
-
(+)-germacrene A synthesis is the committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
-
-
?
additional information
?
-
-
(+)-germacrene A synthesis is the committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
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-
?
additional information
?
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sesquiterpene hydrocarbon profile of leaf extracts, overview
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-
?
additional information
?
-
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sesquiterpene hydrocarbon profile of leaf extracts, overview
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-
?
