4.2.3.20: (R)-limonene synthase
This is an abbreviated version!
For detailed information about (R)-limonene synthase, go to the full flat file.
Word Map on EC 4.2.3.20
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4.2.3.20
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monoterpene
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citrus
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terpene
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orange
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peel
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+-limonene
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linalool
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gpp
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schizonepeta
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tenuifolia
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mentha
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digitatum
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beta-pinene
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lavandula
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angustifolia
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spicata
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frugivores
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labiatae
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neryl
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lavender
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gamma-terpinene
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isoprene
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drug development
- 4.2.3.20
-
monoterpene
- citrus
-
terpene
- orange
- peel
-
+-limonene
- linalool
- gpp
-
schizonepeta
- tenuifolia
-
mentha
- digitatum
- beta-pinene
-
lavandula
- angustifolia
- spicata
-
frugivores
- labiatae
-
neryl
- lavender
- gamma-terpinene
- isoprene
- drug development
Reaction
Synonyms
(+)-limonene synthase, (+)-LS, (R)-limonene synthase, CitMTSE1, CitMTSE2, Cl(+)LIMS1, Cl(+)LIMS2, d-limonene synthase, D-limonene synthase 2, dLMS, LaLIMS, limonene synthase, LIMS, LS3
ECTree
4.2.3.20 (R)-limonene synthaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 4.2.3.20 - (R)-limonene synthase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
geranyl diphosphate
(1R,5R)-(+)-alpha-pinene + diphosphate
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?
geranyl diphosphate
D-limonene + diphosphate
Nepeta tenuifolia
single step in plants
D-limonene shows cancer preventative and cancer therapeutic activities in vitro and in vivo, its modulates apoptosis-related genes and proteins in cultured cells
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?
geranyl diphosphate
(+)-(R)-limonene + diphosphate
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high stereoselectivity, 98.4% of (+)-product
?
geranyl diphosphate
(+)-(R)-limonene + diphosphate
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product is exclusively R-(+)-limonene
?
geranyl diphosphate
(R)-limonene + diphosphate
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products are 39% (R)-limonene, 22% terpinolene, 16% (1R,5S)-camphene, 14% (1R,5R)-(+)-alpha-pinene, 8% betamyrcene and traces of alpha-phellandrene. Product pattern changes markedly to 46% limonene, 9% terpinolene, 23% alpha-pinene, 5% beta-myrcene and 4% alpha-phellandrene, when Mn2+ is supplied instead of Mg2+
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?
additional information
?
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no substrates: farnesyl diphosphate, geranylgeranyl diphosphate
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?
additional information
?
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no substrates: farnesyl diphosphate, geranylgeranyl diphosphate
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?
additional information
?
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Nepeta tenuifolia
a concomitant increase in the level of apoptosis-related protein B-cell lymphoma protein 2 and decreases in the levels of Bcl-2 antagonist of cell death and phosphorylated c-Jun N-terminal kinase are observed in limonene-producing cells
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?
