4.2.3.150: cembrene A synthase

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For detailed information about cembrene A synthase, go to the full flat file.

Reaction

Synonyms

CAS, DtcycB

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.3 Acting on phosphates

                4.2.3.150 cembrene A synthase

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Results	in table
2	AA Sequence
3	Cloned(Commentary)
1	KM Value [mM]
4	Metals/Ions
2	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
8	Organism
2	pH Optimum
10	Protein Variants
2	Purification (Commentary)
3	Reaction
7	Reference
2	Source Tissue
15	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 4.2.3.150 - cembrene A synthase

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SYSTEMATIC NAME

IUBMB Comments

geranylgeranyl-diphosphate diphosphate-lyase [(R)-cembrene-A-forming]

Requires Mg2+. Isolated from the bacterium Streptomyces sp. SANK 60404. This trifunctional enzyme, which contains a [4Fe-4S] cluster, also produces (R)-nephthenol and (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol. See EC 4.2.3.149, nephthenol synthase and EC 4.2.3.151, pentamethylcyclopentadecatrienol synthase.