4.2.3.147: pimaradiene synthase
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For detailed information about pimaradiene synthase, go to the full flat file.
Reaction
Synonyms
monofunctional pimaradiene synthase 1, PbmPIM1, PcmPIM1
ECTree
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Engineering
Engineering on EC 4.2.3.147 - pimaradiene synthase
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T696I
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mutation leads to a dramatic increase in reaction complexity. Product outcome is shifted from the tricyclic pimara-7,15-diene to a rearranged tetracycle, aphidicol-15-ene. Products are about 20% pimara-7,15-diene plus 80% aphidicol-15-ene