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4.2.3.140: cis-abienol synthase

This is an abbreviated version!
For detailed information about cis-abienol synthase, go to the full flat file.

Word Map on EC 4.2.3.140

Reaction

(13E)-8alpha-hydroxylabd-13-en-15-yl diphosphate
=
cis-abienol
+
diphosphate

Synonyms

AbCAS, AbdiTPS4, CAS, cis-abienol synthase, NtABS, TPS4, Z-abienol synthase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.140 cis-abienol synthase

Engineering

Engineering on EC 4.2.3.140 - cis-abienol synthase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
D402A/D404A
D621A
monofunctional class I protein variant, mutant produces trace amounts of copalyl diphosphate plus labda-13-en-8,15-diol
additional information
lab-scale cultivation and pilot-scale cultivation setup of transgenic cell wall-deficient Chlamydomonas reinhardtii strain TN72-TPS4 recombinantly expressing enzyme TPS4, for establishment of industrial production of abietol, method evaluation, overview