4.2.3.131: miltiradiene synthase
This is an abbreviated version!
For detailed information about miltiradiene synthase, go to the full flat file.
Word Map on EC 4.2.3.131
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4.2.3.131
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diterpenoids
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salvia
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diterpene
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tanshinones
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miltiorrhiza
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synthases
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copalyl
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triptolide
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wilfordii
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tripterygium
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hairy
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carnosol
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glandular
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ent-cpp
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lamiaceae
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jasmonate
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labdane-related
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cyclases
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ferruginol
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benthamiana
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trichome
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cosy
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one-hybrid
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synthesis
- 4.2.3.131
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diterpenoids
- salvia
-
diterpene
- tanshinones
- miltiorrhiza
- synthases
-
copalyl
- triptolide
- wilfordii
-
tripterygium
-
hairy
- carnosol
-
glandular
-
ent-cpp
- lamiaceae
- jasmonate
-
labdane-related
- cyclases
- ferruginol
- benthamiana
- trichome
-
cosy
-
one-hybrid
- synthesis
Reaction
Synonyms
ent-kaurene synthase-like, IrTPS4, kaurene synthase-like, kaurene synthase-like 1, kaurene synthase-like 2, KSL, KSL1, KSL2, KSL3, RoSKL1, RoSKL2, SfKSL, SmiKSL, SmMDS, TPS4, TwTPS27v2
ECTree
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Engineering
Engineering on EC 4.2.3.131 - miltiradiene synthase
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D391G/D392G
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the mutant converts only (+)-copalyl diphosphate but not ent- or syn-copalyl diphosphate
D611G/D612G
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the mutant converts geranylgeranyl diphosphate to ent-copalyl diphosphate
additional information
RNAi targeting of TwTPS27v2 is carried out reduces the transcript level of TwTPS27v2 to about 30%, with no reduction in the levels of the related TPS-b subfamily members TwTPS22v2, TwTPS23v2, TwTPS32 and TwTPS33, triptolide accumulation is decreased by about 40%
additional information
-
RNAi targeting of TwTPS27v2 is carried out reduces the transcript level of TwTPS27v2 to about 30%, with no reduction in the levels of the related TPS-b subfamily members TwTPS22v2, TwTPS23v2, TwTPS32 and TwTPS33, triptolide accumulation is decreased by about 40%