4.2.3.128: beta-cubebene synthase

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For detailed information about beta-cubebene synthase, go to the full flat file.

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Synonyms

(Z)-beta-cubebene/alpha-copaene synthase, caryophyllene/cubebene synthase, Cop4, CoTPS2, CsSesquiTPS1, Mg25, sesquiterpene synthase, TPS2, VvShirazTPS-Y2, VvTPS

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.3 Acting on phosphates

4.2.3.128 beta-cubebene synthase

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Results	in table
1	Activating Compound
5	AA Sequence
6	Cloned(Commentary)
12	General Information
4	KM Value [mM]
1	Localization
10	Metals/Ions
13	Natural Substrates/ Products (Substrates)
8	Organism
1	Pathway
3	pH Optimum
4	pH Range
6	Protein Variants
1	Purification (Commentary)
3	Reaction
8	Reference
13	Source Tissue
21	Substrates and Products (Substrate)
3	Subunits
13	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 4.2.3.128 - beta-cubebene synthase

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(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, beta-cubebene-forming)

Isolated from the fungus Coprinus cinereus. The enzyme also forms (+)-delta-cadinene, beta-copaene, (+)-sativene and traces of several other sequiterpenoids [2-4]. It is found in many higher plants such as Magnolia grandiflora (Southern Magnolia) together with germacrene A [1]. See EC 4.2.3.13, (+)-delta-cadinene synthase, EC 4.2.3.127, beta-copaene synthase, EC 4.2.3.129, (+)-sativene synthase, and EC 4.2.3.23, germacrene A synthase.