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4.2.3.127: beta-copaene synthase

This is an abbreviated version!
For detailed information about beta-copaene synthase, go to the full flat file.

Reaction

(2E,6E)-farnesyl diphosphate
=
beta-copaene
+
diphosphate

Synonyms

Cop4, CoTPS2, sesquiterpene synthase, TPS2

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.127 beta-copaene synthase

Temperature Range

Temperature Range on EC 4.2.3.127 - beta-copaene synthase

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TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
additional information
lowering the reaction temperature from 25°C to 4°C increases the selectivity of Cop4 for (-)-germacrene D. Increasing the reaction temperature to 37°C has the opposite effect and decreases the fidelity of Cop4. At this temperature Cop4 generates a relative larger fraction of products beta-cubebene, sativene delta-cadinene, and beta-copaene that are derived from a cadinyl cation intermediate