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4.2.3.12: 6-pyruvoyltetrahydropterin synthase

This is an abbreviated version!
For detailed information about 6-pyruvoyltetrahydropterin synthase, go to the full flat file.

Word Map on EC 4.2.3.12

Reaction

7,8-dihydroneopterin 3'-triphosphate
=
6-pyruvoyl-5,6,7,8-tetrahydropterin
 +
Triphosphate

Synonyms

2-amino-4-oxo-6-(erythro-1',2',3'-trihydroxypropyl)-7,8-dihydroxypterdine triphosphate lyase, 6-(1,2-dioxopropyl)tetrahydropterin synthase, 6-carboxy-5,6,7,8-tetrahydropterin synthase, 6-pyruvoyl tetrahydrobiopterin synthase, 6-pyruvoyl-tetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase paralog, 6-pyruvoyltetrahydropterin synthase [16-cysteine] (human clone lamda HSY2 gene PCBD subunit), 6-pyruvoyltetrahydropterin synthase [25-glutamine] (human clone lambdaHSY2 gene PCBD subunit), 6-pyruvoyltetrahydropterin synthase [de-57-valine] (human clone lambdaHSY2 gene PCBD subunit), 6-pyruvoyltetrahydropterin synthase-like protein, EC 4.6.1.10, ePTPS, PH0634, PPH4 synthase, PPH4S, protein purple, PTP synthase, PTPS, PTPS homologue, PTPS-III, PTS, pyruvoyltetrahydropterin synthase, SCO 6650, synthase, 6-pyruvoyltetrahydropterin, synthase, 6-pyruvoyltetrahydropterin [16-cysteine] (human clone lamda HSY2 gene PCBD subunit), synthase, 6-pyruvoyltetrahydropterin [25-glutamine] (human clone lamdaHSY2 gene PCBD subunit), synthase, 6-pyruvoyltetrahydropterin [87-leucine] (human clone lamdaHSY2 gene PCBD subunit), synthase, 6-pyruvoyltetrahydropterin [de-57-valine] (human clone lambdaHSY2 gene PCBD subunit)

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.12 6-pyruvoyltetrahydropterin synthase

Organism

Organism on EC 4.2.3.12 - 6-pyruvoyltetrahydropterin synthase

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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
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UniProt
Manually annotated by BRENDA team
transgenic mouse with a replacement of the Pts allele, encoding the 6-pyruvoyl-tetrahydropterin synthase, by an in-frame insertion in exon 2 with the beta-galactosidase gene generating a fusion protein containing the N-terminal 35 amino acids for 6-pyruvoyl-tetrahydropterin synthase followed by the beta-galactosidase
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Manually annotated by BRENDA team
strain PCC 7942
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team