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4.2.3.12: 6-pyruvoyltetrahydropterin synthase

This is an abbreviated version!
For detailed information about 6-pyruvoyltetrahydropterin synthase, go to the full flat file.

Word Map on EC 4.2.3.12

Reaction

7,8-dihydroneopterin 3'-triphosphate
=
6-pyruvoyl-5,6,7,8-tetrahydropterin
+
Triphosphate

Synonyms

2-amino-4-oxo-6-(erythro-1',2',3'-trihydroxypropyl)-7,8-dihydroxypterdine triphosphate lyase, 6-(1,2-dioxopropyl)tetrahydropterin synthase, 6-carboxy-5,6,7,8-tetrahydropterin synthase, 6-pyruvoyl tetrahydrobiopterin synthase, 6-pyruvoyl-tetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase, 6-pyruvoyltetrahydropterin synthase paralog, 6-pyruvoyltetrahydropterin synthase [16-cysteine] (human clone lamda HSY2 gene PCBD subunit), 6-pyruvoyltetrahydropterin synthase [25-glutamine] (human clone lambdaHSY2 gene PCBD subunit), 6-pyruvoyltetrahydropterin synthase [de-57-valine] (human clone lambdaHSY2 gene PCBD subunit), 6-pyruvoyltetrahydropterin synthase-like protein, EC 4.6.1.10, ePTPS, PH0634, PPH4 synthase, PPH4S, protein purple, PTP synthase, PTPS, PTPS homologue, PTPS-III, PTS, pyruvoyltetrahydropterin synthase, SCO 6650, synthase, 6-pyruvoyltetrahydropterin, synthase, 6-pyruvoyltetrahydropterin [16-cysteine] (human clone lamda HSY2 gene PCBD subunit), synthase, 6-pyruvoyltetrahydropterin [25-glutamine] (human clone lamdaHSY2 gene PCBD subunit), synthase, 6-pyruvoyltetrahydropterin [87-leucine] (human clone lamdaHSY2 gene PCBD subunit), synthase, 6-pyruvoyltetrahydropterin [de-57-valine] (human clone lambdaHSY2 gene PCBD subunit)

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.3 Acting on phosphates
                4.2.3.12 6-pyruvoyltetrahydropterin synthase

Molecular Weight

Molecular Weight on EC 4.2.3.12 - 6-pyruvoyltetrahydropterin synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
15855
-
x * 15855, calculation from nucleotide sequence
15899
-
3 * 15899, electron-ionization mass spectrometry
16000
16199
-
x * 16199, mutant protein R16C, electrospray mass spectrometry
16224
-
x * 16224, mutant protein R25Q, electrospray mass spectrometry
16254
-
6 * 16254, electron-ionization mass spectrometry
16255
16257
-
5 * 16257, electrospray ionization-mass spectrometry
16500
17000
17208
-
4 * 17208, electrospray ionization mass spectrometry
18500
-
4 * 18500, SDS-PAGE
19000
21000
* 21000, SDS-PAGE
37500
47000
-
3 * 47000, SDS-PAGE
68000
72000
-
native PAGE
83000
85000 - 87000
-
gel filtration
90000
gel filtration
97000
-
6 * 97000, SDS-PAGE