4.2.3.11: sabinene-hydrate synthase
This is an abbreviated version!
For detailed information about sabinene-hydrate synthase, go to the full flat file.
Reaction
Synonyms
cyclase, sabinene hydrate, EC 4.6.1.9, sabinene hydrate cyclase, sabinene-hydrate synthase, TPS6, Tps7
ECTree
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Engineering
Engineering on EC 4.2.3.11 - sabinene-hydrate synthase
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I346N
mutation to the corresponding residue in isoform Tps6. Mutation alters the stereospecificity to that of TPS6. (1S,2S,4R)-(E)-sabinene hydrate is still the main product of this mutant, but I346N also produces the (4S)-enantiomers of (E)-sabinene hydrate and (Z)-sabinene hydrate
N350I
mutation to the corresponding residue in isoform Tps7. Mutation alters the stereospecificity to that of TPS7, mutant produces only the (1S,2S,4R)-enantiomer of (E)-sabinene hydrate