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4.2.2.5: chondroitin AC lyase

This is an abbreviated version!
For detailed information about chondroitin AC lyase, go to the full flat file.

Word Map on EC 4.2.2.5

Reaction

[1,3-beta-D-glucuronic acid-1,4-beta-D-hexosylamine]n
= n-1 4-deoxy-beta-D-gluc-4-enuronosyl-1,4-beta-D-hexosylamine +
[1,3-beta-D-glucuronic acid-1,4-beta-D-hexosylamine]

Synonyms

A-Chase, AC I lyase, c-ACI, c-ACII, ChnAC, chon-AC-lyase, ChonAC, chondroitin AC eliminase, chondroitin AC I lyase, Chondroitin AC lyase, chondroitin ACII lyase, chondroitin lyase AC, chondroitin sulfate lyase, chondroitinase, chondroitinase AC, chondroitinase ACI, chondroitinase ACII, ChSase-AC, EC 4.2.99.6, F-Chase, lyase, chondroitin AC, Pedsa_3808, PL8A

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.2 Acting on polysaccharides
                4.2.2.5 chondroitin AC lyase

Activating Compound

Activating Compound on EC 4.2.2.5 - chondroitin AC lyase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
20 mM, 2fold activation
chondroitin 4-sulfate
2.5fold induction of enzyme expression
Na+
100 mM, 2fold activation
additional information
-
not affected by Mg2+, Mn2+, Ca2+, Co2+, and EDTA
-