4.2.2.19: chondroitin B lyase
This is an abbreviated version!
For detailed information about chondroitin B lyase, go to the full flat file.
Word Map on EC 4.2.2.19
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4.2.2.19
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dermatan
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glycosaminoglycans
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proteoglycans
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disaccharide
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heparan
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heparinum
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flavobacterium
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heparitinase
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hyaluronidase
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decorin
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oversulfated
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4-sulphate
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nonsulfated
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l-iduronic
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keratanase
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4.2.2.5
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idoa
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hexasaccharide
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galactosaminoglycans
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analysis
- 4.2.2.19
- dermatan
- glycosaminoglycans
- proteoglycans
- disaccharide
- heparan
- heparinum
-
flavobacterium
- heparitinase
- hyaluronidase
- decorin
-
oversulfated
-
4-sulphate
-
nonsulfated
-
l-iduronic
- keratanase
-
4.2.2.5
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idoa
- hexasaccharide
- galactosaminoglycans
- analysis
Reaction
Synonyms
ChnB, ChonB, chondroitin B lyase, chondroitinase B, CslB, lyase, chondroitin B
ECTree
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Natural Substrates Products on EC 4.2.2.19 - chondroitin B lyase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
dermatan sulfate
?
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substrate is involved in activities related to metastasis
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?
additional information
?
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enzyme inhibits endothelial and melanoma proliferation and invasion, but to a lesser extent than chondroitin AC lyase, EC 4.2.2.5, enzyme has no effect on gelatinase excretion by melanoma cells, enzyme does not activate caspase-3 activity and apoptosis in melanoma and endothelial cells
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?
