4.2.2.11: guluronate-specific alginate lyase
This is an abbreviated version!
For detailed information about guluronate-specific alginate lyase, go to the full flat file.
Word Map on EC 4.2.2.11
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4.2.2.11
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lyases
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degradation
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klebsiella
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unsaturated
-
polysaccharide
-
endolytic
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pneumoniae
-
depolymerization
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synthesis
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aerogenes
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flavobacterium
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4.2.2.3
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tetrasaccharide
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algae
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terrestrial
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mannuronate
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sphingomonas
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biomass
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biofuel production
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agriculture
-
industry
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food industry
- 4.2.2.11
- lyases
- degradation
-
klebsiella
- unsaturated
- polysaccharide
-
endolytic
- pneumoniae
-
depolymerization
- synthesis
- aerogenes
- flavobacterium
-
4.2.2.3
- tetrasaccharide
- algae
-
terrestrial
-
mannuronate
- sphingomonas
- biomass
- biofuel production
- agriculture
- industry
- food industry
Reaction
Synonyms
A1m, A9mC, A9mL, A9mT, Alg17C, Alg2A, Alg7D, AlgB, alginase II, alginate (poly-alpha-L-guluronate) lyase, alginate lyase, AlgL, AlgL5, AlgMytC, alkaliphilic alginate lyase, ALY, Aly-SJ02, Aly1, Aly5, AlyA, AlyA1PL7, AlyA5, AlyD, AlyDW11, AlyE, AlyQ, AlyV5, AXE80_11190, endo-type alginate lyase, guluronate lyase, KJ-2 alginate lyase, L-guluronan lyase, L-guluronate lyase, lyase, polyguluronate, Oal17A, oligoalginate lyase, poly(1,4-alpha-L-guluronide)lyase, poly(alpha-L-guluronate) lyase, poly-alpha-L-guluronate lyase, polyguluronate-specific alginate lyase, polyMG-specific alginate lyase, V12B01_09446, V12B01_24274, WP_053404615, xadAly7B
ECTree
4.2.2.11 guluronate-specific alginate lyaseAdvanced search results
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Reference on EC 4.2.2.11 - guluronate-specific alginate lyase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nakagawa, A.; Ozaki, T.; Chubachi, K.; Hosoyama, T.; Okubo, T.; Iyobe, S.; Suzuki, T.
An effective method for isolating alginate lyase-producing Bacillus sp. ATB-1015 strain and purification and characterization of the lyase
J. Appl. Microbiol.
84
328-335
1998
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) ATB-1015
Boyd, J.; Turvey, J.R.
Isolation of poly-alpha-L-guluronate lyase from Klebsiella aerogenes
Carbohydr. Res.
57
163-171
1977
Klebsiella aerogenes
Gacesa, P.
Alginate-modifying enzymes. A proposed unified mechanism of action for the lyases and epimerases
FEBS Lett.
212
199-202
1987
Klebsiella aerogenes
-
Lange, B.; Wingender, J.; Winkler, U.K.
Isolation and characterization of an alginate lyase from Klebsiella aerogenes
Arch. Microbiol.
152
302-308
1989
Klebsiella aerogenes
Hisano, T.; Nishimura, M.; Yamashita, T.; Imanaka, T.; Muramatsu, T.; Kimura, A.; Murata, K.
A simple method for determination of substrate specificity of alginate lyases
J. Ferment. Bioeng.
78
182-184
1994
Bacillus sp. (in: Bacteria), Flavobacterium sp.
-
Nibu, Y.; Satoh, T.; Nishi, Y.; Takeuchi, T.; Murata, K.; Kusakabe, I.
Purification and characterization of extracellular alginate lyase from Enterobacter cloacae M-1
Biosci. Biotechnol. Biochem.
59
632-637
1995
Enterobacter cloacae, Enterobacter cloacae M-1intracellular
Takeuchi, T.; Nibu, Y.; Murata, K.; Kusakabe, I.
Purification and characterization of endo poly (alpha-L-guluronate) lyase in the enzyme system from Flavobacterium multivorum
Food Sci. Technol. Int.
3
22-26
1997
Sphingobacterium multivorum, Sphingobacterium multivorum K-11
-
Matsubara, Y.; Kawada, R.; Iwasaki, K.; Oda, T.; Muramatsu, T.
Extracellular poly(alpha-L-guluronate)lyase from Corynebacterium sp.: purification, characteristics, and conformational properties
J. Protein Chem.
17
29-36
1998
Corynebacterium sp., Corynebacterium sp. ALY-1
Matsubara, Y.; Iwasaki, K.I.; Muramatsu, T.
Action of poly(alpha-L-guluronate) lyase from Corynebacterium sp. ALY-1 strain on saturated oligoguluronates
Biosci. Biotechnol. Biochem.
62
1055-1060
1998
Corynebacterium sp., Corynebacterium sp. ALY-1
Ostgaard, K.; Knutsen, S.H.; Dyrset, N.; Aasen, I.M.
Production and characterization of guluronate lyase from Klebsiella pneumoniae for applications in seaweed biotechnology
Enzyme Microb. Technol.
15
756-763
1993
Klebsiella pneumoniae
Shimokawa, T.; Yoshida, S.; Kusakabe, I.
Effects of Unsaturated Uronic Acid Residues at Non-reducing End on Bond Cleavage Frequency of Poly(1,4-?-L-guluronide) Lyase from Enterobacter cloacae M-1.
Biosci. Biotechnol. Biochem.
62
164-166
1998
Enterobacter cloacae, Sphingobacterium multivorum, Enterobacter cloacae M-1intracellular, Sphingobacterium multivorum K-11
Wong, T.Y.; Preston, L.A.; Schiller, N.L.
Alginate lyase: review of major sources and enzyme characteristics, structure-function analysis, biological roles, and applications
Annu. Rev. Microbiol.
54
289-340
2000
Enterobacter cloacae, Bacillus sp. (in: Bacteria), Corynebacterium sp., Corynebacterium sp. (Q9RB42), Sphingobacterium multivorum, Klebsiella pneumoniae, Pseudomonas sp., Pseudomonas aeruginosa, Sargassum sp., Vibrio harveyi, Vibrio sp., Pseudoalteromonas elyakovii (Q9Z6D6), Vibrio harveyi AL-128
Iwamoto, Y.; Araki, R.; Iriyama, K.; Oda, T.; Fukuda, H.; Hayashida, S.; Muramatsu, T.
Purification and characterization of bifunctional alginate lyase from Alteromonas sp. strain no. 272 and its action on saturated oligomeric substrates
Biosci. Biotechnol. Biochem.
65
133-142
2001
Alteromonas sp., Alteromonas sp. 272
Miyazaki, M.; Obata, J.; Iwamoto, Y.; Oda, T.; Muramatsu, T.
Calcium-sensitive extracellular poly(alpha-L-guluronate) lyase from a marine bacterium Pseudomonas sp. strain F6: Purification and some properties
Fish. Sci.
67
956-964
2001
Pseudomonas sp., Pseudomonas sp. F6
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Yamasaki, M.; Moriwaki, S.; Hashimoto, W.; Mikami, B.; Murata, K.
Crystallization and preliminary X-ray analysis of alginate lyase, a member of family PL-7, from Pseudomonas aeruginosa
Acta Crystallogr. Sect. D
59
1499-1501
2003
Pseudomonas aeruginosa
Yamasaki, M.; Ogura, K.; Moriwaki, S.; Hashimoto, W.; Murata, K.; Mikami, B.
Crystallization and preliminary X-ray analysis of alginate lyases A1-II and A1-II' from Sphingomonas sp. A1
Acta Crystallogr. Sect. F
61
288-290
2005
Sphingomonas sp.
Osawa, T.; Matsubara, Y.; Muramatsu, T.; Kimura, M.; Kakuta, Y.
Crystal structure of the alginate (poly alpha-l-guluronate) lyase from Corynebacterium sp. at 1.2 A resolution
J. Mol. Biol.
345
1111-1118
2005
Corynebacterium sp. (Q9RB42)
Coulson-Thomas, Y.M.; Coulson-Thomas, V.J.; Filippo, T.R.; Mortara, R.A.; da Silveira, R.B.; Nader, H.B.; Porcionatto, M.A.
Adult bone marrow-derived mononuclear cells expressing chondroitinase AC transplanted into CNS injury sites promote local brain chondroitin sulphate degradation
J. Neurosci. Methods
171
19-29
2008
Agarivorans sp.
Matsushima, R.; Danno, H.; Uchida, M.; Ishihara, K.; Suzuki, T.; Kaneniwa, M.; Ohtsubo, Y.; Nagata, Y.; Tsuda, M.
Analysis of extracellular alginate lyase and its gene from a marine bacterial strain, Pseudoalteromonas atlantica AR06
Appl. Microbiol. Biotechnol.
86
567-576
2010
Pseudoalteromonas atlantica (D1MX66), Pseudoalteromonas atlantica AR06 (D1MX66)
Ochiai, A.; Yamasaki, M.; Mikami, B.; Hashimoto, W.; Murata, K.
Crystal structure of exotype alginate lyase Atu3025 from Agrobacterium tumefaciens
J. Biol. Chem.
285
24519-24528
2010
Agrobacterium tumefaciens (A9CEJ9)
Uchimura, K.; Miyazaki, M.; Nogi, Y.; Kobayashi, T.; Horikoshi, K.
Cloning and sequencing of alginate lyase genes from deep-sea strains of Vibrio and Agarivorans and characterization of a new Vibrio enzyme
Mar. Biotechnol.
12
526-533
2010
Vibrio sp. (C4TJD2), Vibrio sp. (C4TJD3), Vibrio sp. (C4TJD4), Vibrio sp. A9m (C4TJD2), Vibrio sp. A9m (C4TJD3), Vibrio sp. A9m (C4TJD4)
Inoue, A.; Mashino, C.; Kodama, T.; Ojima, T.
Protoplast preparation from Laminaria japonica with recombinant alginate lyase and cellulase
Mar. Biotechnol.
13
256-263
2011
Haliotis discus hannai
Li, L.; Jiang, X.; Guan, H.; Wang, P.; Guo, H.
Three alginate lyases from marine bacterium Pseudomonas fluorescens HZJ216: Purification and characterization
Appl. Biochem. Biotechnol.
164
305-317
2011
Pseudomonas fluorescens, Pseudomonas fluorescens HZJ216
Li, L.; Jiang, X.; Guan, H.; Wang, P.
Preparation, purification and characterization of alginate oligosaccharides degraded by alginate lyase from Pseudomonas sp. HZJ 216
Carbohydr. Res.
346
794-800
2011
Pseudomonas sp., Pseudomonas sp. HZJ 216
Tang, J.; Zhou, Q.; Chu, H.; Nagata, S.
Characterization of alginase and elicitor-active oligosaccharides from Gracilibacillus A7 in alleviating salt stress for Brassica campestris L
J. Agric. Food Chem.
59
7896-7901
2011
Gracilibacillus sp.
Singh, R.; Gupta, V.; Kumari, P.; Kumar, M.; Reddy, C.; Prasad, K.; Jha, B.
Purification and partial characterization of an extracellular alginate lyase from Aspergillus oryzae isolated from brown seaweed
J. Appl. Phycol.
23
755-762
2011
Aspergillus oryzae
-
Tondervik, A.; Klinkenberg, G.; Aarstad, O.; Drablos, F.; Ertesvag, H.; Ellingsen, T.; Skjak-Brak, G.; Valla, S.; Sletta, H.
Isolation of mutant alginate lyases with cleavage specificity for Di-guluronic acid linkages
J. Biol. Chem.
285
35284-35292
2010
Klebsiella pneumoniae
Park, H.; Kam, N.; Lee, E.; Kim, H.
Cloning and characterization of a novel oligoalginate lyase from a newly isolated bacterium Sphingomonas sp. MJ-3
Mar. Biotechnol.
14
189-202
2012
Sphingomonas sp. (G1EH67), Sphingomonas sp. MJ-3 (G1EH67)
Li, J.; Dong, S.; Song, J.; Li, C.; Chen, X.; Xie, B.; Zhang, Y.
Purification and characterization of a bifunctional alginate lyase from Pseudoalteromonas sp. SM0524
Mar. Drugs
9
109-123
2011
Pseudoalteromonas sp.
Kim, H.T.; Chung, J.H.; Wang, D.; Lee, J.; Woo, H.C.; Choi, I.G.; Kim, K.H.
Depolymerization of alginate into a monomeric sugar acid using Alg17C, an exo-oligoalginate lyase cloned from Saccharophagus degradans 2-40
Appl. Microbiol. Biotechnol.
93
2233-2239
2012
Saccharophagus degradans (Q21FJ0), Saccharophagus degradans 2-40 / ATCC 43961 (Q21FJ0)
Lee, S.I.; Choi, S.H.; Lee, E.Y.; Kim, H.S.
Molecular cloning, purification, and characterization of a novel polyMG-specific alginate lyase responsible for alginate MG block degradation in Stenotrophomas maltophilia KJ-2
Appl. Microbiol. Biotechnol.
95
1643-1653
2012
Stenotrophomonas maltophilia (I6P4V6), Stenotrophomonas maltophilia KJ-2 (I6P4V6)
Farrell, E.K.; Tipton, P.A.
Functional characterization of AlgL, an alginate lyase from Pseudomonas aeruginosa
Biochemistry
51
10259-10266
2012
Pseudomonas aeruginosa
Kim, H.T.; Ko, H.J.; Kim, N.; Kim, D.; Lee, D.; Choi, I.G.; Woo, H.C.; Kim, M.D.; Kim, K.H.
Characterization of a recombinant endo-type alginate lyase (Alg7D) from Saccharophagus degradans
Biotechnol. Lett.
34
1087-1092
2012
Saccharophagus degradans
Wang, Y.; Guo, E.W.; Yu, W.G.; Han, F.
Purification and characterization of a new alginate lyase from a marine bacterium Vibrio sp.
Biotechnol. Lett.
35
703-708
2013
Vibrio sp., Vibrio sp. QY105
Kam, N.; Park, Y.J.; Lee, E.Y.; Kim, H.S.
Molecular identification of a polyM-specific alginate lyase from Pseudomonas sp. strain KS-408 for degradation of glycosidic linkages between two mannuronates or mannuronate and guluronate in alginate
Can. J. Microbiol.
57
1032-1041
2011
Pseudomonas sp. (G9J5R3), Pseudomonas sp. KS-408 (G9J5R3)
Dou, W.; Wei, D.; Li, H.; Li, H.; Rahman, M.M.; Shi, J.; Xu, Z.; Ma, Y.
Purification and characterisation of a bifunctional alginate lyase from novel Isoptericola halotolerans CGMCC 5336
Carbohydr. Polym.
98
1476-1482
2013
Isoptericola halotolerans, Isoptericola halotolerans (AB489222), Isoptericola halotolerans CGMCC5336 (AB489222), Isoptericola halotolerans CGMCC 5336
SilChenko, A.; Kusaikin, M.; Zakharenko, A.; Zvyagintseva, T.
Isolation from the marine mollusk Lambis sp. and catalytic properties of an alginate lyase with rare substrate specificity
Chem. Nat. Compd.
49
215-218
2013
Lambis sp. AAB-2014
-
Thomas, F.; Lundqvist, L.C.; Jam, M.; Jeudy, A.; Barbeyron, T.; Sandstroem, C.; Michel, G.; Czjzek, M.
Comparative characterization of two marine alginate lyases from Zobellia galactanivorans reveals distinct modes of action and exquisite adaptation to their natural substrate
J. Biol. Chem.
288
23021-23037
2013
Zobellia galactanivorans (G0KZG8), Zobellia galactanivorans (G0L2Y1), Zobellia galactanivorans, Zobellia galactanivorans DSM 12802 (G0KZG8)
Park, D.; Jagtap, S.; Nair, S.K.
Structure of a PL17 family alginate lyase demonstrates functional similarities among exotype depolymerases
J. Biol. Chem.
289
8645-8655
2014
Saccharophagus degradans (Q21FJ0)
Sim, S.J.; Baik, K.S.; Park, S.C.; Choe, H.N.; Seong, C.N.; Shin, T.S.; Woo, H.C.; Cho, J.Y.; Kim, D.
Characterization of alginate lyase gene using a metagenomic library constructed from the gut microflora of abalone
J. Ind. Microbiol. Biotechnol.
39
585-593
2012
uncultured bacterium (G3LI08)
Huang, L.; Zhou, J.; Li, X.; Peng, Q.; Lu, H.; Du, Y.
Characterization of a new alginate lyase from newly isolated Flavobacterium sp. S20
J. Ind. Microbiol. Biotechnol.
40
113-122
2013
Flavobacterium sp. (G9CHX6)
Sakatoku, A.; Tanaka, D.; Nakamura, S.
Purification and characterization of an alkaliphilic alginate lyase AlgMytC from Saccharophagus sp. Myt-1
J. Microbiol. Biotechnol.
23
872-877
2013
Saccharophagus sp. Myt-1 (L8B3Z6)
Ravanal, M.; Sharma, S.; Gimpel, J.; Reveco-Urzua, F.; Overland, M.; Horn, S.; Lienqueo, M.
The role of alginate lyases in the enzymatic saccharification of brown macroalgae, Macrocystis pyrifera and Saccharina latissima
Algal Res.
26
287-293
2017
Microbulbifer sp. 6532A (E7FLJ9), Pseudoalteromonas elyakovii (Q9Z6D6)
-
Badur, A.H.; Jagtap, S.S.; Yalamanchili, G.; Lee, J.K.; Zhao, H.; Rao, C.V.
Alginate lyases from alginate-degrading Vibrio splendidus 12B01 are endolytic
Appl. Environ. Microbiol.
81
1865-1873
2015
Vibrio splendidus (A3UR44), Vibrio splendidus (A3UT33), Vibrio splendidus 12B01 (A3UR44), Vibrio splendidus 12B01 (A3UT33)
Han, W.; Gu, J.; Cheng, Y.; Liu, H.; Li, Y.; Li, F.
Novel alginate lyase (Aly5) from a polysaccharide-degrading marine bacterium, Flammeovirga sp. strain MY04 effects of module truncation on biochemical characteristics, alginate degradation patterns, and oligosaccharide-yielding properties
Appl. Environ. Microbiol.
82
364-374
2016
Flammeovirga sp. MY04 (A0A0M4N5N7)
Cheng, Y.; Wang, D.; Gu, J.; Li, J.; Liu, H.; Li, F.; Han, W.
Biochemical characteristics and variable alginate-degrading modes of a novel bifunctional endolytic alginate lyase
Appl. Environ. Microbiol.
83
e01608
2017
Flammeovirga sp. MY04 (A0A1B1FUW4)
Yagi, H.; Fujise, A.; Itabashi, N.; Ohshiro, T.
Purification and characterization of a novel alginate lyase from the marine bacterium Cobetia sp. NAP1 isolated from brown algae
Biosci. Biotechnol. Biochem.
80
2338-2346
2016
Cobetia sp. NAP1
Zhu, B.; Ni, F.; Sun, Y.; Yao, Z.
Expression and characterization of a new heat-stable endo-type alginate lyase from deep-sea bacterium Flammeovirga sp. NJ-04
Extremophiles
21
1027-1036
2017
Flammeovirga sp. NJ-04 (A0A1Z2QRE2)
Yu, Z.; Zhu, B.; Wang, W.; Tan, H.; Yin, H.
Characterization of a new oligoalginate lyase from marine bacterium Vibrio sp.
Int. J. Biol. Macromol.
112
937-942
2018
Vibrio sp. W13 (A0A0F7KQI4)
Zhu, B.; Ni, F.; Ning, L.; Sun, Y.; Yao, Z.
Cloning and characterization of a new pH-stable alginate lyase with high salt tolerance from marine Vibrio sp. NJ-04
Int. J. Biol. Macromol.
115
1063-1070
2018
Vibrio sp. NJ-04 (A0A1Z2QRD5)
Zhu, B.; Tan, H.; Qin, Y.; Xu, Q.; Du, Y.; Yin, H.
Characterization of a new endo-type alginate lyase from Vibrio sp. W13
Int. J. Biol. Macromol.
75
330-337
2015
Vibrio sp. W13 (A0A0A1DYR7)
Tavafi, H.; Abdi-Ali, A.; Ghadam, P.; Gharavi, S.
Screening of alginate lyase-producing bacteria and optimization of media compositions for extracellular alginate lyase production
Iran. Biomed. J.
21
48-56
2017
Bacillus sp. TAG8 (A0A0H3WC39)
Yagi, H.; Fujise, A.; Itabashi, N.; Ohshiro, T.
Characterization of a novel endo-type alginate lyase derived from Shewanella sp. YH1
J. Biochem.
163
341-350
2018
Shewanella sp. YH1
Zhu, B.; Ning, L.; Jiang, Y.; Ge, L.
Biochemical characterization and degradation pattern of a novel endo-type bifunctional alginate lyase AlyA from marine bacterium Isoptericola halotolerans
Mar. Drugs
16
258
2018
Isoptericola halotolerans (A0A346FH09), Isoptericola halotolerans NJ-05 (A0A346FH09)
Zhu, Y.; Wu, L.; Chen, Y.; Ni, H.; Xiao, A.; Cai, H.
Characterization of an extracellular biofunctional alginate lyase from marine Microbulbifer sp. ALW1 and antioxidant activity of enzymatic hydrolysates
Microbiol. Res.
182
49-58
2016
Microbulbifer sp. ALW1
Pei, X.; Chang, Y.; Shen, J.
Cloning, expression and characterization of an endo-acting bifunctional alginate lyase of marine bacterium Wenyingzhuangia fucanilytica
Protein Expr. Purif.
154
44-51
2019
Wenyingzhuangia fucanilytica (A0A1B1Y7V0)
Manns, D.; Nyffenegger, C.; Saake, B.; Meyer, A.
Impact of different alginate lyases on combined cellulase-lyase saccharification of brown seaweed
RSC Adv.
6
45392-45401
2016
Sphingobacterium multivorum, Flavobacterium sp. S20 (G9CHX6), Sphingomonas sp. A1 (Q75WP3)
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