4.2.1.91: arogenate dehydratase
This is an abbreviated version!
For detailed information about arogenate dehydratase, go to the full flat file.
Word Map on EC 4.2.1.91
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4.2.1.91
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chorismate
-
l-tyrosine
-
phenylpyruvate
-
mutase
-
phenylpropanoids
-
shikimate
-
monofunctional
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4-hydroxyphenylpyruvate
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p-protein
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pseudomonad
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overflow
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dahp
-
7-phosphate
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industry
- 4.2.1.91
- chorismate
- l-tyrosine
- phenylpyruvate
- mutase
-
phenylpropanoids
- shikimate
-
monofunctional
- 4-hydroxyphenylpyruvate
- p-protein
-
pseudomonad
-
overflow
- dahp
- 7-phosphate
- industry
Reaction
Synonyms
AdT, ADT/PDT, ADT1, ADT2, ADT3, ADT4, ADT5, ADT6, AGN dehydratase, arogenate dehydratase, arogenate dehydratase isoform 1, arogenate dehydratase isoform 2, arogenate dehydratase isoform 3, arogenate dehydratase isoform 4, arogenate dehydratase isoform 5, arogenate dehydratase isoform 6, arogenate dehydratase/prephenate dehydratase, arogenate dehydratase1, arogenate dehydratase2, arogenate dehydratase3, At1g08250, At1g11790, At2g27820, At3g07630, At3g44720, At5g22630, AtADT1, AtADT2, AtADT3, AtADT4, AtADT5, AtADT6, carboxycyclohexadienyl dehydratase, CDT, cyclohexadienyl dehydratase, dehydratase ADT3, F25C20.4 protein, Mtr1, prephenate dehydratase
ECTree
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Reference on EC 4.2.1.91 - arogenate dehydratase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Xia, T.; Ahmad, S.; Zhao, G.; Jensen, R.A.
A single cyclohexadienyl dehydratase specifies the prephenate dehydratase and arogenate dehydratase components of one of two independent pathways to L-phenylalanine in Erwinia herbicola
Arch. Biochem. Biophys.
286
461-465
1991
Pantoea agglomerans
Bonner, C.A.; Fischer, R.S.; Schmidt, R.R.; Miller, P.W.; Jensen, R.A.
Distinctive enzymes of aromatic amino acid biosynthesis that are highly conserved in land plants are also present in the chlorophyte alga Chlorella sorokiniana
Plant Cell Physiol.
36
1013-1022
1995
Chlorella sorokiniana, Nicotiana sylvestris
-
Zamir, L.O.; Tiberio, R.; Fiske, M.; Berry, A.; Jensen, R.A.
Enzymatic and nonenzymatic dehydration reactions of L-arogenate
Biochemistry
24
1607-1612
1985
Brevundimonas diminuta, Pseudomonas aeruginosa
Ahmad, S.; Jensen, R.A.
A simple spectrophotometric assay for arogenate dehydratase
Anal. Biochem.
163
107-111
1987
Pantoea agglomerans, no activity in Acinetobacter calcoaceticus
Fischer, R.; Jensen, R.
Arogenate dehydratase
Methods Enzymol.
142
495-502
1987
Brevundimonas diminuta, Euglena gracilis, Pseudomonas aeruginosa, Xanthomonas campestris
Siehl, D.L.; Conn, E.E.
Kinetic and regulatory properties of arogenate dehydratase in seedlings of Sorghum bicolor (L.) Moench
Arch. Biochem. Biophys.
260
822-829
1988
Sorghum bicolor, Sorghum bicolor ATX2752
Zamir, L.O.; Tiberio, R.; Devor, K.A.; Sauriol, F.; Ahmad, S.; Jensen, R.A.
Structure of D-prephenyllactate. A carboxycyclohexadienyl metabolite from Neurospora crassa
J. Biol. Chem.
263
17284-17290
1988
Klebsiella pneumoniae
Zhao, G.; Xia, T.; Fischer, R.S.; Jensen, R.A.
Cyclohexadienyl dehydratase from Pseudomonas aeruginosa. Molecular cloning of the gene and characterization of the gene product
J. Biol. Chem.
267
2487-2493
1992
Pseudomonas aeruginosa, Pseudomonas aeruginosa (Q01269)
Zhao, G.; Xia, T.; Aldrich, H.; Jensen, R.A.
Cyclohexadienyl dehydratase from Pseudomonas aeruginosa is a periplasmic protein
J. Gen. Microbiol.
139
807-813
1993
Pseudomonas aeruginosa (Q01269), Pseudomonas aeruginosa
Obmolova, G.; Teplyakov, A.; Xia, T.; Jensen, R.
Preliminary crystallographic study of cyclohexadienyl dehydratase from Pseudomonas aeruginosa
J. Mol. Biol.
232
992-994
1993
Pseudomonas aeruginosa
Tam, R.; Saier, M.H., Jr.
A bacterial periplasmic receptor homologue with catalytic activity: cyclohexadienyl dehydratase of Pseudomonas aeruginosa is homologous to receptors specific for polar amino acids
Res. Microbiol.
144
165-169
1993
Pseudomonas aeruginosa (Q01269), Pseudomonas aeruginosa
Cho, M.H.; Corea, O.R.; Yang, H.; Bedgar, D.L.; Laskar, D.D.; Anterola, A.M.; Moog-Anterola, F.A.; Hood, R.L.; Kohalmi, S.E.; Bernards, M.A.; Kang, C.; Davin, L.B.; Lewis, N.G.
Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases
J. Biol. Chem.
282
30827-30835
2007
Arabidopsis thaliana (O22241), Arabidopsis thaliana (Q9FNJ8), Arabidopsis thaliana (Q9SA96), Arabidopsis thaliana (Q9SGD6), Arabidopsis thaliana (Q9SSE7), Arabidopsis thaliana (Q9ZUY3)
Yamada, T.; Matsuda, F.; Kasai, K.; Fukuoka, S.; Kitamura, K.; Tozawa, Y.; Miyagawa, H.; Wakasa, K.
Mutation of a rice gene encoding a phenylalanine biosynthetic enzyme results in accumulation of phenylalanine and tryptophan
Plant Cell
20
1316-1329
2008
Oryza sativa (A8CF65), Oryza sativa
Wakasa, K.; Ishihara, A.
Metabolic engineering of the tryptophan and phenylalanine biosynthetic pathways in rice
Plant Biotechnol.
26
523-533
2009
Oryza sativa
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Maeda, H.; Shasany, A.K.; Schnepp, J.; Orlova, I.; Taguchi, G.; Cooper, B.R.; Rhodes, D.; Pichersky, E.; Dudareva, N.
RNAi suppression of arogenate dehydratase1 reveals that phenylalanine is synthesized predominantly via the arogenate pathway in petunia petals
Plant Cell
22
832-849
2010
Petunia x hybrida (D3U715), Petunia x hybrida (D3U716), Petunia x hybrida (D3U717), Petunia x hybrida
Bross, C.D.; Corea, O.R.; Kaldis, A.; Menassa, R.; Bernards, M.A.; Kohalmi, S.E.
Complementation of the pha2 yeast mutant suggests functional differences for arogenate dehydratases from Arabidopsis thaliana
Plant Physiol. Biochem.
49
882-890
2011
Arabidopsis thaliana (O22241), Arabidopsis thaliana (Q9FNJ8), Arabidopsis thaliana (Q9SA96), Arabidopsis thaliana (Q9SGD6), Arabidopsis thaliana (Q9SSE7), Arabidopsis thaliana (Q9ZUY3), Arabidopsis thaliana
Corea, O.R.; Ki, C.; Cardenas, C.L.; Kim, S.J.; Brewer, S.E.; Patten, A.M.; Davin, L.B.; Lewis, N.G.
Arogenate dehydratase isoenzymes profoundly and differentially modulate carbon flux into lignins
J. Biol. Chem.
287
11446-11459
2012
Arabidopsis thaliana
Corea, O.R.; Bedgar, D.L.; Davin, L.B.; Lewis, N.G.
The arogenate dehydratase gene family: towards understanding differential regulation of carbon flux through phenylalanine into primary versus secondary metabolic pathways
Phytochemistry
82
22-37
2012
Arabidopsis thaliana
Bross, C.D.; Howes, T.R.; Abolhassani Rad, S.; Kljakic, O.; Kohalmi, S.E.
Subcellular localization of Arabidopsis arogenate dehydratases suggests novel and non-enzymatic roles
J. Exp. Bot.
68
1425-1440
2017
Arabidopsis thaliana (Q9FNJ8), Arabidopsis thaliana (Q9SA96), Arabidopsis thaliana (Q9SGD6), Arabidopsis thaliana (Q9SSE7), Arabidopsis thaliana (Q9ZUY3), Arabidopsis thaliana Col-0 (Q9FNJ8), Arabidopsis thaliana Col-0 (Q9SA96), Arabidopsis thaliana Col-0 (Q9SGD6), Arabidopsis thaliana Col-0 (Q9SSE7), Arabidopsis thaliana Col-0 (Q9ZUY3)
Chen, Q.; Man, C.; Li, D.; Tan, H.; Xie, Y.; Huang, J.
Arogenate dehydratase isoforms differentially regulate anthocyanin biosynthesis in Arabidopsis thaliana
Mol. Plant
9
1609-1619
2016
Arabidopsis thaliana (O22241), Arabidopsis thaliana (Q9FNJ8), Arabidopsis thaliana (Q9SA96), Arabidopsis thaliana (Q9SGD6), Arabidopsis thaliana (Q9SSE7), Arabidopsis thaliana (Q9ZUY3), Arabidopsis thaliana
Para, A.; Muhammad, D.; Orozco-Nunnelly, D.A.; Memishi, R.; Alvarez, S.; Naldrett, M.J.; Warpeha, K.M.
The dehydratase ADT3 affects ROS homeostasis and cotyledon development
Plant Physiol.
172
1045-1060
2016
Arabidopsis thaliana (Q9ZUY3), Arabidopsis thaliana
Hoehner, R.; Marques, J.V.; Ito, T.; Amakura, Y.; Budgeon, A.D.; Weitz, K.; Hixson, K.K.; Davin, L.B.; Kirchhoff, H.; Lewis, N.G.
Reduced arogenate dehydratase expression ramifications for photosynthesis and metabolism
Plant Physiol.
177
115-131
2018
Arabidopsis thaliana (O22241), Arabidopsis thaliana (Q9FNJ8), Arabidopsis thaliana (Q9SA96), Arabidopsis thaliana (Q9SGD6), Arabidopsis thaliana (Q9ZUY3), Arabidopsis thaliana
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