4.2.1.75: uroporphyrinogen-III synthase
This is an abbreviated version!
For detailed information about uroporphyrinogen-III synthase, go to the full flat file.
Word Map on EC 4.2.1.75
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4.2.1.75
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porphyria
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erythropoietic
-
heme
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photosensitivity
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5-aminolevulinic
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tetrapyrrole
-
coproporphyrins
-
delta-aminolevulinic
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ferrochelatase
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pbgase
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mutilate
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erythrodontia
-
transfusion-dependent
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protoporphyria
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hypertrichosis
-
urologists
-
coproporphyrinogen
-
aymaras
-
amerindian
- 4.2.1.75
- porphyria
-
erythropoietic
- heme
-
photosensitivity
-
5-aminolevulinic
- tetrapyrrole
- coproporphyrins
-
delta-aminolevulinic
-
ferrochelatase
-
pbgase
-
mutilate
-
erythrodontia
-
transfusion-dependent
- protoporphyria
-
hypertrichosis
-
urologists
- coproporphyrinogen
-
aymaras
-
amerindian
Reaction
Synonyms
CobA/HemD, Hydroxymethylbilane hydrolyase [cyclizing], hydroxymethylbilane hydrolyase, cyclizing, Isomerase, uroporphyrinogen, Porphobilinogenase, Synthase, uroporphyrinogen III co-, U3S, URO synthase, uro'gen III synthase, URO-synthase, UROIIIS, Uroporphyrinogen III co-synthase, Uroporphyrinogen III cosynthase, Uroporphyrinogen III synthase, Uroporphyrinogen isomerase, Uroporphyrinogen-III cosynthase, Uroporphyrinogen-III cosynthetase, uroporphyrinogen-III-synthase, UROS
ECTree
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KCat KM Value
KCat KM Value on EC 4.2.1.75 - uroporphyrinogen-III synthase
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1
kcat/Km less than 1 1/sec*mM, mutant enzyme C73R, pH and temperature not specified in the publication
3700
Hydroxymethylbilane
mutant enzyme C73R/A69E, pH and temperature not specified in the publication
15000
Hydroxymethylbilane
wild type enzyme, pH and temperature not specified in the publication
16000
Hydroxymethylbilane
mutant enzyme C73R/L43D, pH and temperature not specified in the publication