4.2.1.74: medium-chain-enoyl-CoA hydratase

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For detailed information about medium-chain-enoyl-CoA hydratase, go to the full flat file.

Word Map on EC 4.2.1.74

4.2.1.74

peroxisomal

beta-oxidation

enoyl-coas

d-3-hydroxyacyl-coas

trans-2-enoyl-coa

2,4-dienoyl-coa

acyl-coas

tropicalis

polyunsaturated

stereochemical

3r-hydroxyacyl-coas

epimerase

unsaturated

epimerization

mfe-2s

3-ketoacyl-coa

unliganded

bulkier

thiolase

monofunctional

2-trans-enoyl-coa

dehydrogenate

spiral

l-isomers

crotonase

two-domain

n-domain

straight-chain

Reaction

Synonyms

2-enoyl-CoA hydratase 2, D-3-hydroxyacyl-CoA dehydratase, ECH2, enoyl-CoA hydratase, hydratase, long-chain enoyl coenzyme A, long chain enoyl coenzyme A hydratase, long-chain enoyl coenzyme A hydratase, long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase, long-chain-enoyl-CoA hydratase

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.74 medium-chain-enoyl-CoA hydratase

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Results	in table
1	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
9	Inhibitors
1	Ki Value [mM]
10	KM Value [mM]
5	Localization
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
6	Organism
8	Pathway
2	pH Optimum
1	pH Range
4	Purification (Commentary)
1	Reaction
1	Reaction Type
6	Reference
7	Source Tissue
1	Specific Activity [micromol/min/mg]
2	Storage Stability
20	Substrates and Products (Substrate)
1	Subunits
12	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 4.2.1.74 - medium-chain-enoyl-CoA hydratase

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medium-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase

Acts in the reverse direction. The best substrate for the porcine enzyme is oct-2-enoyl-CoA. Unlike EC 4.2.1.17 enoyl-CoA hydratase, it does not act on crotonoyl-CoA.