4.2.1.51: prephenate dehydratase

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For detailed information about prephenate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.51

4.2.1.51

l-phenylalanine

arogenate

l-tyrosine

dahp

l-phe

7-phosphate

cyclohexadienyl

l-tyr

3-deoxy-d-arabino-heptulosonate

feedback-inhibited

5.4.99.5

synthesis

industry

Reaction

Synonyms

ADT1, ADT2, ADT6, AroQ, chorismate mutase prephenate dehydratase, chorismate mutase-prephenate dehydratase, Chorismate mutase/prephenate dehydratase, CM-PD, CM/PDT/PDHG, Cmut1, CM�PDT, Ct-PDT, cyclohexydienyl dehydratase, dehydratase, prephenate, Gmut11, Gmut9, MjPDT, monofunctional prephenate dehydratase, MtbPDT, P-protein, P-protein dehydratase, PDT, PDT protein, PheA, PpADT-B, PpADT-C, PpADT-G, prephenate dehydratase, prephenate dehydratase 1, Sa-PDT

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.51 prephenate dehydratase

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Results	in table
40	Activating Compound
37529	AA Sequence
5	Application
1	CAS Registry Number
23	Cloned(Commentary)
5	Crystallization (Commentary)
1	Expression
11	General Information
2	General Stability
2	IC50 Value
65	Inhibitors
7	kcat/KM [mM/s]
7	Ki Value [mM]
47	KM Value [mM]
3	Localization
2	Metals/Ions
43	Molecular Weight [Da]
48	Natural Substrates/ Products (Substrates)
284	Organism
7	Pathway
18	PDB ID
11	pH Optimum
3	pH Range
1	pH Stability
42	Protein Variants
23	Purification (Commentary)
5	Reaction
3	Reaction Type
65	Reference
3	Source Tissue
34	Specific Activity [micromol/min/mg]
8	Storage Stability
103	Substrates and Products (Substrate)
32	Subunits
54	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
4	Temperature Stability [°C]
26	Turnover Number [1/s]

Purification

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Purification on EC 4.2.1.51 - prephenate dehydratase

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5 entries

bifunctional enzyme, chorismate mutase:prephenate dehydratase

3 entries

bifunctional enzyme, prephenate dehydratase-arogenate dehydratase

Pantoea agglomerans

33892

catalytic and regulatory domains of prephenate dehydratase, individually cloned in the NdeI/XhoI sites of pET23a vector and expressed in Escherichia coli BL21(DE3)

Mycobacterium tuberculosis

665625

gel filtration

Archaeoglobus fulgidus

O30012

692260

gel filtration, recombinant protein

Mycobacterium tuberculosis

P9WIC3

695038

gel filtration, SDS-PAGE

Oryza sativa

A8CF65, Q6Z3Y3

694629

Ni-NTA affinity column chromatography, and Superdex 200 gel filtration

Streptococcus mutans

Q8DUV6

730200

partial

Salmonella enterica subsp. enterica serovar Typhimurium

33888, 33889

recombinant His-tagged wild-type and mutant enzymes from Escherichia coli

Corynebacterium glutamicum

649516

recombinant wild-type prephenate dehydratase domain and the mutant enzymes

Escherichia coli

649980