4.2.1.47: GDP-mannose 4,6-dehydratase
This is an abbreviated version!
For detailed information about GDP-mannose 4,6-dehydratase, go to the full flat file.
Word Map on EC 4.2.1.47
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4.2.1.47
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alginate
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fucosylation
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gdp-l-fucose
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mucoid
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l-fucose
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gdp-4-keto-6-deoxy-d-mannose
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gdp-mannuronic
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gdp-d-rhamnose
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phosphomannomutase
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fucosyltransferase
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gdp-4-keto-6-deoxymannose
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d-rhamnose
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synthesis
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biotechnology
- 4.2.1.47
- alginate
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fucosylation
- gdp-l-fucose
- mucoid
- l-fucose
- gdp-4-keto-6-deoxy-d-mannose
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gdp-mannuronic
- gdp-d-rhamnose
- phosphomannomutase
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fucosyltransferase
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gdp-4-keto-6-deoxymannose
- d-rhamnose
- synthesis
- biotechnology
Reaction
Synonyms
ATCV-1GMD, bceN, Dm-gmd, GDP-alpha-D-mannose 4,6-dehydratase, GDP-D-mannose 4,6-dehydratase, GDP-D-mannose 4-oxido-6-reductase, GDP-D-mannose dehydratase, GDP-D-mannose-4,6-dehydratase, GDP-mannose 4, 6-dehydratase, GDP-mannose 4,6 dehydratase, GDP-mannose 4,6-dehydratase, GDP-mannose dehydratase, GDP-mannose dehydrogenase, GDP-mannose-4,6-dehydratase, GMD, GMDS, guanosine 5'-diphosphate-D-mannose 4,6-dehydratase, Guanosine 5'-diphosphate-D-mannose oxidoreductase, Guanosine diphosphomannose 4,6-dehydratase, Guanosine diphosphomannose oxidoreductase, L-GMD, M-GMD, MUR1, ORF13.7, PBCV-1 GMD, S-GMD
ECTree
4.2.1.47 GDP-mannose 4,6-dehydrataseAdvanced search results
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results (Substrates Products
Substrates Products on EC 4.2.1.47 - GDP-mannose 4,6-dehydratase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
GDP-4-dehydro-6-deoxy-D-mannose
GDP-D-rhamnose
i.e., GDP-6-deoxy-D-lyxo-hexos-4-ulose
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-
?
GDP-alpha-D-mannose
GDP-4-dehydro-alpha-D-rhamnose + H2O
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-
-
?
GDP-D-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
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-
-
-
?
GDP-D-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
Paramecium bursaria Chlorella virus-1
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-
-
-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
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ATCV-1GMD has no reductase activity
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-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
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-
-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
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-
-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
Paramecium bursaria Chlorella virus-1
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ATCV-1GMD has no reductase activity
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-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
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key regulatory enzyme controlling alginate biosynthesis in mucoid strain of pseudomonas aeruginosa
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-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
is a bifunctional 4,6-dehydratase, and a stereospecific 4-reductase. A conserved amino acid side chain (Arg185) may be crucial for orienting substrate and cofactor
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-
?
GDP-mannose
GDP-4-dehydro-6-deoxy-D-mannose + H2O
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stereochemistry and mechanism
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?
additional information
?
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first step in the de novo pathway of GDP-L-fucose biosynthesis
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?
additional information
?
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first step in the de novo pathway of GDP-L-fucose biosynthesis
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?
additional information
?
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co-expression and activities of GDP-mannose 4,6-dehydratase and GDP-L-fucose synthetase lead toptoduction of GDP-L-fucose
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-
?
additional information
?
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co-expression and activities of GDP-mannose 4,6-dehydratase and GDP-L-fucose synthetase lead toptoduction of GDP-L-fucose
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-
?
additional information
?
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key step in the de novo pathway of GDP-L-fucose biosynthesis
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?
additional information
?
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key step in the de novo pathway of GDP-L-fucose biosynthesis
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?
additional information
?
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enzyme of the constitutively active de novo pathway for biosynthesis of GDP-L-fucose
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?
additional information
?
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Paramecium bursaria chlorella virus
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enzyme is involved in modification of structural proteins
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?
additional information
?
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enzyme of the constitutively active de novo pathway for biosynthesis of GDP-L-fucose
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-
?
