4.2.1.47: GDP-mannose 4,6-dehydratase

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For detailed information about GDP-mannose 4,6-dehydratase, go to the full flat file.

Reaction

Synonyms

ATCV-1GMD, bceN, Dm-gmd, GDP-alpha-D-mannose 4,6-dehydratase, GDP-D-mannose 4,6-dehydratase, GDP-D-mannose 4-oxido-6-reductase, GDP-D-mannose dehydratase, GDP-D-mannose-4,6-dehydratase, GDP-mannose 4, 6-dehydratase, GDP-mannose 4,6 dehydratase, GDP-mannose 4,6-dehydratase, GDP-mannose dehydratase, GDP-mannose dehydrogenase, GDP-mannose-4,6-dehydratase, GMD, GMDS, guanosine 5'-diphosphate-D-mannose 4,6-dehydratase, Guanosine 5'-diphosphate-D-mannose oxidoreductase, Guanosine diphosphomannose 4,6-dehydratase, Guanosine diphosphomannose oxidoreductase, L-GMD, M-GMD, MUR1, ORF13.7, PBCV-1 GMD, S-GMD

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.47 GDP-mannose 4,6-dehydratase

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Results	in table
6	Activating Compound
28462	AA Sequence
3	Application
1	CAS Registry Number
22	Cloned(Commentary)
18	Cofactor
4	Crystallization (Commentary)
33	Disease/ Diagnostics
9	General Information
3	General Stability
34	Inhibitors
2	kcat/KM [mM/s]
6	Ki Value [mM]
17	KM Value [mM]
1	Localization
7	Metals/Ions
21	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
57	Organism
1	Oxidation Stability
14	Pathway
66	PDB ID
9	pH Optimum
4	pH Range
4	Protein Variants
19	Purification (Commentary)
3	Reaction
1	Reaction Type
54	Reference
17	Source Tissue
9	Specific Activity [micromol/min/mg]
5	Storage Stability
73	Substrates and Products (Substrate)
16	Subunits
57	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
9	Turnover Number [1/s]

Oxidation Stability

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Oxidation Stability on EC 4.2.1.47 - GDP-mannose 4,6-dehydratase

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OXIDATION STABILITY

ORGANISM

UNIPROT

LITERATURE

enzyme is not very sensitive to oxidative inactivation. Specific activity activity of GDP-mannose dehydrogense increases with dissolved oxygen tension of up to 25% of air saturation and maintains the maximal value up to at least 70% of air saturation

Pseudomonas aeruginosa

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665895