4.2.1.47: GDP-mannose 4,6-dehydratase
This is an abbreviated version!
For detailed information about GDP-mannose 4,6-dehydratase, go to the full flat file.
Word Map on EC 4.2.1.47
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4.2.1.47
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alginate
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fucosylation
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gdp-l-fucose
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mucoid
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l-fucose
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gdp-4-keto-6-deoxy-d-mannose
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gdp-mannuronic
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gdp-d-rhamnose
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phosphomannomutase
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fucosyltransferase
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gdp-4-keto-6-deoxymannose
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d-rhamnose
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synthesis
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biotechnology
- 4.2.1.47
- alginate
-
fucosylation
- gdp-l-fucose
- mucoid
- l-fucose
- gdp-4-keto-6-deoxy-d-mannose
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gdp-mannuronic
- gdp-d-rhamnose
- phosphomannomutase
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fucosyltransferase
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gdp-4-keto-6-deoxymannose
- d-rhamnose
- synthesis
- biotechnology
Reaction
Synonyms
ATCV-1GMD, bceN, Dm-gmd, GDP-alpha-D-mannose 4,6-dehydratase, GDP-D-mannose 4,6-dehydratase, GDP-D-mannose 4-oxido-6-reductase, GDP-D-mannose dehydratase, GDP-D-mannose-4,6-dehydratase, GDP-mannose 4, 6-dehydratase, GDP-mannose 4,6 dehydratase, GDP-mannose 4,6-dehydratase, GDP-mannose dehydratase, GDP-mannose dehydrogenase, GDP-mannose-4,6-dehydratase, GMD, GMDS, guanosine 5'-diphosphate-D-mannose 4,6-dehydratase, Guanosine 5'-diphosphate-D-mannose oxidoreductase, Guanosine diphosphomannose 4,6-dehydratase, Guanosine diphosphomannose oxidoreductase, L-GMD, M-GMD, MUR1, ORF13.7, PBCV-1 GMD, S-GMD
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Application
Application on EC 4.2.1.47 - GDP-mannose 4,6-dehydratase
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biotechnology
repression of the GMD gene is thus very useful for deleting immunogenic total fucose residues and facilitating the production of pharmaceutical glycoproteins in plants
synthesis
GMD knockout CHO cells are ideal host cells for the manufacture of completely non-fucosylated therapeutic antibodies and completely O-fucose-negative therapeutics as well
synthesis
repression of the GMD gene is thus very useful for deleting immunogenic total fucose residues and facilitating the production of pharmaceutical glycoproteins in plants