4.2.1.33: 3-isopropylmalate dehydratase

This is an abbreviated version!
For detailed information about 3-isopropylmalate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.33

4.2.1.33

aconitase

ipmis

jannaschii

homoaconitase

glucosinolate

bcaas

citramalate

2-isopropylmalate

Reaction

Synonyms

3-isopropylmalate dehydratase, 3-isopropylmalate isomerase, Alpha-IPM isomerase, alpha-isopropylmalate isomerase, beta-Isopropylmalate dehydratase, dehydratase,beta-isopropylmalate, IPM dehydratase, IPM isomerase, IPMI, IPMI SSU1, isopropylmalate dehydratase, isopropylmalate isomerase, LEU1S, leuC, LeuCD, LeuD, MJ0499, More, SOI10, Superoxide-inducible protein 10

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.33 3-isopropylmalate dehydratase

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Results	in table
4	Activating Compound
81275	AA Sequence
1	CAS Registry Number
8	Cloned(Commentary)
5	Crystallization (Commentary)
3	Expression
17	General Information
11	General Stability
39	Inhibitors
10	KM Value [mM]
7	Localization
6	Metals/Ions
9	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
223	Organism
5	Pathway
18	PDB ID
9	pH Optimum
5	pH Range
2	pH Stability
5	Protein Variants
7	Purification (Commentary)
8	Reaction
3	Reaction Type
30	Reference
11	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
41	Substrates and Products (Substrate)
15	Subunits
62	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 4.2.1.33 - 3-isopropylmalate dehydratase

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(2R,3S)-3-isopropylmalate

(2S)-2-isopropylmalate

Pyrococcus horikoshii

O59393

the isopropylmalate isomerase small subunit of the hyperthermophilic archaea Pyrococcus horikoshii (PhIPMI-s) functions as isopropylmalate isomerase in the leucine biosynthesis pathway, and as homoaconitase (HACN) in the lysine biosynthesis pathway via alpha-aminoadipic acid

722946

(2R,3S)-3-isopropylmalate

2-isopropylmaleate + H2O

2 entries

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2 entries

(2S)-2-isopropylmalate + H2O

(2R,3S)-3-isopropylmalate

2 entries

2-isopropylmaleate + H2O

5 entries