4.2.1.31: maleate hydratase
This is an abbreviated version!
For detailed information about maleate hydratase, go to the full flat file.
Reaction
(R)-malate=
Maleate +
H2O
Synonyms
D-malate hydro-lyase, HbzIJ, malease, maleic-acid hydratase
ECTree
Inhibitors
Inhibitors on EC 4.2.1.31 - maleate hydratase
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(2R,3S)-tartaric acid
-
Ki: 3.15 mM
2,2-dimethylsuccinate
-
Ki: 0.025 mM
acetylenedicarboxylate
-
Ki: 4.55 mM
Ba2+
-
36% inhibition at 100 mM, formation of substrate/product precipitate
Ca2+
-
20% inhibition at 250 mM
CdCl2
-
24% inhibition at 2 mM
D-citramalate
-
Ki: 0.083 mM
EDTA
-
80% inhibition at 1 mM
Maleate
-
important for commercial use, liquid/crystal two phase systems developed to minimize effect
Mg2+
-
16% inhibition at 250 mM
nitrilo-triacetic acid
-
complete inhibition at 1 mM
oxaloacetic acid
-
Ki: 8.22 mM
phosphate
-
92% inhibition at 100 mM
RuCl3
-
up to 100% inhibition at 0.25 mM, dependent on sequence of addition
ZnSO4
-
complete inhibition at 1 mM
CuSO4
-
32% inhibition at 2 mM
CuSO4
-
60% inhibition at 1 mM
D-malate
-
important for commercial use, liquid/crystal two phase systems developed to minimize effect
Fe2(SO4)3
-
41% inhibition at 2 mM
Fe2(SO4)3
-
67% inhibition at 1 mM
HgCl2
-
25% inhibition at 2 mM
HgCl2
-
complete inhibition at 1 mM
iodoacetamide
-
-
iodoacetamide
-
complete inhibition at 1 mM
o-phenanthroline
-
-
o-phenanthroline
-
65% inhibition at 1 mM
p-chloromercuribenzoate
-
-
p-chloromercuribenzoate
-
75% inhibition at 1 mM
p-chloromercuribenzoate
-
complete inhibition at 0.1 mM
additional information
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additional information
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additional information
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4.2.1.31 maleate hydratase
results (
results (
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