4.2.1.30: glycerol dehydratase

This is an abbreviated version!
For detailed information about glycerol dehydratase, go to the full flat file.

Reaction

Synonyms

B12-dependent enzyme glycerol dehydratase, B12-dependent glycerol dehydratase, B12-independent GDH, B12-independent glycerol dehydratase, dehydratase, glycerol, DhaB, DhaB1, DhaBCE, DhaC, DhaE, GDH, GDHt, glycerol dehdydrogenase, glycerol dehydrase, glycerol dehydratase, glycerol hydro-lyase, glycerol hydrolyase, KpG, KpGDHt, vitamin B12-independent glycerol dehydratase

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.30 glycerol dehydratase

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Results	in table
43	Activating Compound
411	AA Sequence
22	Application
1	CAS Registry Number
27	Cloned(Commentary)
63	Cofactor
5	Crystallization (Commentary)
13	General Information
4	General Stability
48	Inhibitors
9	kcat/KM [mM/s]
98	KM Value [mM]
32	Metals/Ions
49	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
176	Organism
2	Oxidation Stability
3	Pathway
12	PDB ID
15	pH Optimum
3	pH Range
4	pH Stability
38	Protein Variants
17	Purification (Commentary)
14	Reaction
1	Reaction Type
117	Reference
27	Specific Activity [micromol/min/mg]
3	Storage Stability
222	Substrates and Products (Substrate)
32	Subunits
66	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
2	Temperature Range [°C]
13	Temperature Stability [°C]
12	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 4.2.1.30 - glycerol dehydratase

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

390

(R)-1,2-Propanediol

Klebsiella pneumoniae

Q59476; O08505; Q59475

37°C, pH 7.0, linked complex of the fusion protein of alpha- and beta-subunits and the gamma subunit

747370

660 - 1400

glycerol

3 entries

5.1 - 130

meso-2,3-butanediol

2 entries

840 - 1500

pentane-1,2-diol

3 entries

660

glycerol

Klebsiella pneumoniae

A8CIU9

mutant enzyme KpG60, at pH 6.0 and 37°C

729463

710

glycerol

Klebsiella pneumoniae

A8CIU9

wild type enzyme, at pH 6.0 and 37°C

729463

1400

glycerol

Klebsiella pneumoniae

A8CIU9

mutant enzyme KpG525, at pH 6.0 and 37°C

729463

5.1

meso-2,3-butanediol

Klebsiella pneumoniae

Q59476; O08505; Q59475

37°C, pH 7.0, mutant enzyme T200S

747370

130

meso-2,3-butanediol

Klebsiella pneumoniae

Q59476; O08505; Q59475

37°C, pH 7.0, linked complex of the fusion protein of alpha- and beta-subunits and the gamma subunit

747370

840

pentane-1,2-diol

Klebsiella pneumoniae

A8CIU9

wild type enzyme, at pH 6.0 and 37°C

729463

1200

pentane-1,2-diol

Klebsiella pneumoniae

A8CIU9

mutant enzyme KpG60, at pH 6.0 and 37°C

729463

1500

pentane-1,2-diol

Klebsiella pneumoniae

A8CIU9

mutant enzyme KpG525, at pH 6.0 and 37°C

729463