4.2.1.22: cystathionine beta-synthase
This is an abbreviated version!
For detailed information about cystathionine beta-synthase, go to the full flat file.
Word Map on EC 4.2.1.22
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4.2.1.22
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h2s
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sulfide
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homocystinuria
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hyperhomocysteinemia
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artery
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spacer
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corticobasal
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candida
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mthfr
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carotid
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folate
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transsulfuration
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conidia
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cajal
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nahs
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dextrose
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methylenetetrahydrofolate
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bismuth
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hallucinations
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anamorphic
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palsy
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supranuclear
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charles
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remethylation
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reisolated
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conidiophore
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gamma-lyase
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biodiversity
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hyaline
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chemoreceptor
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gasotransmitter
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3-mercaptopyruvate
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frontotemporal
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sulfurtransferase
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thromboembolic
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ascospore
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rinsed
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aminooxyacetic
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apraxia
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snrnps
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symptomless
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hydrosulfide
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marxianus
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visuospatial
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5,10-methylenetetrahydrofolate
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voxel-based
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appressoria
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naocl
-
medicine
-
diagnostics
-
ascus
-
phytopathological
-
analysis
- 4.2.1.22
- h2s
- sulfide
- homocystinuria
- hyperhomocysteinemia
- artery
-
spacer
-
corticobasal
- candida
- mthfr
-
carotid
- folate
-
transsulfuration
- conidia
-
cajal
- nahs
- dextrose
- methylenetetrahydrofolate
-
bismuth
- hallucinations
-
anamorphic
- palsy
-
supranuclear
-
charles
-
remethylation
-
reisolated
-
conidiophore
-
gamma-lyase
-
biodiversity
-
hyaline
-
chemoreceptor
-
gasotransmitter
- 3-mercaptopyruvate
-
frontotemporal
- sulfurtransferase
-
thromboembolic
- ascospore
-
rinsed
-
aminooxyacetic
- apraxia
-
snrnps
-
symptomless
- hydrosulfide
- marxianus
-
visuospatial
- 5,10-methylenetetrahydrofolate
-
voxel-based
-
appressoria
- naocl
- medicine
- diagnostics
- ascus
-
phytopathological
- analysis
Reaction
Synonyms
Beta-thionase, CBS, CBS424, CDCP2, CNNM2, Cys4, CysB, cystathionine beta synthase, cystathionine beta-synthase, cystathionine beta-synthase domain-containing protein, cystathionine-beta-synthase, Cysteine synthase, EC 4.2.1.21, hCBS, Hemoprotein H-450, LbrM.17.0230, Methylcysteine synthase, osmoprotectant transporter OpuC, PF1953, PH0267, Serine sulfhydrase, Serine sulfhydrylase, Serine sulphhydrase, TA0289, TM0935, TV1335, yCBS, ytCBS
ECTree
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KCat KM Value
KCat KM Value on EC 4.2.1.22 - cystathionine beta-synthase
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0.17
H2S
cosubstrate L-serine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C
0.005
-
reverse reaction (L-cystathionine hydrolysis), mutant S289A
7.5
L-cystathionine
-
reverse reaction (L-cystathionine hydrolysis), wild-type
0.0006
formation of (2R,2'R)-3,3'-sulfanediylbis(2-aminopropanoic acid), mutant E223G, pH 7.5, 37°C
0.12
L-cysteine
formation of (2R,2'R)-3,3'-sulfanediylbis(2-aminopropanoic acid), wild-type, pH 7.5, 37°C
0.18
L-cysteine
cosubstrate H2O, presence of S-adenosyl-L-methionine, pH 7.4, 37°C
1.3
L-cysteine
formation of L-cystathionine, wild-type, pH 7.5, 37°C
1.5
L-cysteine
formation of L-cystathionine, mutant A70S, pH 7.5, 37°C
1.98
L-cysteine
cosubstrate L-homocysteine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C
8.9
L-cysteine
formation of L-cystathionine, mutant E223G, pH 7.5, 37°C
0.15
formation of L-cystathionine, mutant A70S, pH 7.5, 37°C
0.83
L-homocysteine
formation of L-cystathionine, mutant E223G, pH 7.5, 37°C
2.8
L-homocysteine
mutant D444N, 37°C, pH not specified in the publication
4.71
L-homocysteine
mutant V449G, 37°C, pH not specified in the publication
4.82
L-homocysteine
mutant S500L, 37°C, pH not specified in the publication
5.22
L-homocysteine
mutant K523Sfs?18, 37°C, pH not specified in the publication
5.23
L-homocysteine
mutant P427L, 37°C, pH not specified in the publication
6.02
L-homocysteine
cosubstrate L-cysteine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C
10.56
L-homocysteine
A0A1J9VES8
wild-type, production of H2S, pH 8.2, 37°C
11
L-homocysteine
mutant L540Q, 37°C, pH not specified in the publication
12.74
L-homocysteine
synthesis of L-cystathionine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C
14
L-homocysteine
formation of L-cystathionine, wild-type, pH 7.5, 37°C
0.47
L-serine
cosubstrate H2S, presence of S-adenosyl-L-methionine, pH 7.4, 37°C
0.71
L-serine
mutant K523Sfs?18, 37°C, pH not specified in the publication
7.61
L-serine
synthesis of L-cystathionine, presence of S-adenosyl-L-methionine, pH 7.4, 37°C