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4.2.1.20: tryptophan synthase

This is an abbreviated version!
For detailed information about tryptophan synthase, go to the full flat file.

Word Map on EC 4.2.1.20

Reaction

1-C-(indol-3-yl)glycerol 3-phosphate
=
indole
 +
D-glyceraldehyde 3-phosphate

Synonyms

alpha2beta2 tryptophan synthase, alphaTS, AtTSB1, beta subunit of tryptophan synthase, indoleglycerol phosphate aldolase, It-TSA, L-serine hydro-lyase (adding indoleglycerol-phosphate), L-tryptophan synthetase, PtTSA, Rv1612, synthase, tryptophan, TrB, Trp synthase, Trp synthase beta, TrpA, trpB, TrpB1, TrpB2, TrpB2a, TrpB2i, TrpB2o, TRPS, tryptophan desmolase, tryptophan synthase, tryptophan synthase alpha subunit, tryptophan synthase alpha-subunit, tryptophan synthase alpha2beta2 complex, tryptophan synthase beta, tryptophan synthase beta 1, tryptophan synthase beta subunit, tryptophan synthetase, TS, TSA, TSase, TSB, TSB1, TSbeta

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.20 tryptophan synthase

Specific Activity

Specific Activity on EC 4.2.1.20 - tryptophan synthase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10.53
-
-
110
-
overall activity, purified enzyme complex
1150
-
purified wild-type, beta-reaction, in absence of DL-alpha-glycerol 3-phosphate
119
-
beta-reaction, purified enzyme complex
1310
-
wild-type enzyme, in presence of Na+
1375
-
purified wild-type, reverse alpha-reaction, in presence of DL-alpha-glycerol 3-phosphate
1400
-
wild-type enzyme, in presence of Cs+
1605
-
purified wild-type, reverse alpha-reaction, in absence of DL-alpha-glycerol 3-phosphate
1650
-
mutant K167T, in presence of Cs+
190
-
wild-type enzyme, in presence of guanidinum
2.8
-
indole production from 1-(indol-3-yl)glycerol 3-phosphate
2200
-
mutant D56A, in presence of Cs+
275
-
indole + L-Ser
288
-
purified wild-type, beta-reaction, in presence of DL-alpha-glycerol 3-phosphate
511
-
purified mutant G181P, reverse alpha-reaction, in presence of DL-alpha-glycerol 3-phosphate
520
-
purified mutant G181P, beta-reaction, in absence or presence of DL-alpha-glycerol 3-phosphate
70
-
mutant K167T, in presence of Na+
8.5
-
alpha-reaction, purified enzyme complex
818
-
purified mutant G181P, reverse alpha-reaction, in absence of DL-alpha-glycerol 3-phosphate
85
-
indole + L-Ser
additional information