4.2.1.17: enoyl-CoA hydratase

This is an abbreviated version!
For detailed information about enoyl-CoA hydratase, go to the full flat file.

Reaction

Synonyms

(R)-specific 2-enoyl-CoA hydratase, 2,3-dehydroadipyl-CoA hydratase, 2-enoyl-CoA hydratase, 2-enoyl-CoA hydratase 1, 2-enoyl-CoA hydratase-1, 2-enoyl-hydratase 1, 2-octenoyl coenzyme A hydrase, acyl coenzyme A hydrase, AIM1, AMECH, beta-hydroxyacid dehydrase, beta-hydroxyacyl-CoA dehydrase, CCH/HBCD, classic 2-enoyl-CoA hydratase, crotonase, crotonyl hydrase, crotonyl-CoA hydratase, D-3-hydroxyacyl-CoA dehydratase, DELTA2-enoyl-CoA hydratase-1, ECH, ECH-1, ECH-2, ECH1, ECH2, ECHS1, enol-CoA hydratase, Enoyl coenzyme A hydrase (D), enoyl coenzyme A hydrase (L), enoyl coenzyme A hydratase, enoyl coenzyme A hydratase (L), enoyl coenzyme A hydratase 1, enoyl hydrase, enoyl-CoA hydratase, enoyl-CoA hydratase 1, enoyl-CoA hydratase 2, enoyl-CoA hydratase short chain 1, enoyl-CoA hydratase/isomerase, enoyl-coenzyme A hydratase, enoyl-coenzyme A hydratase/isomerase, FadB', FadRBs, H16_A0461, hydratase, enoyl coenzyme A, mECH-1, MFP2, mitochondrial enoyl coenzyme A hydratase, mitochondrial short-chain enoyl-CoA hydratase, mitochondrial short-chain enoyl-CoA hydratase-1, More, multifunctional enzyme type 1, PaaF, PBE, PBFE, perMFE-1, perMFE-I, peroxisomal bifunctional enzyme, peroxisomal multifunctional enzyme, type 1, R-3-hydroxyacyl-CoA enoyl-CoA hydratase, R-3-hydroxyacyl-CoA enoyl-CoA hydratases, rat peroxisomal multifunctional enzyme type 1, rpMFE1, S-3-hydroxyacyl-CoA enoyl-CoA hydratase, S-3-hydroxyacyl-CoA enoyl-CoA hydratases, SCEH, short chain enoyl coenzyme A hydratase, short-chain enoyl-CoA hydratase, trans-2-enoyl-CoA hydratase, unsaturated acyl-CoA hydratase, YsiA

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.17 enoyl-CoA hydratase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
55218	AA Sequence
3	Application
1	CAS Registry Number
17	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
409	Disease/ Diagnostics
3	Expression
34	General Information
31	Inhibitors
2	kcat/KM [mM/s]
17	Ki Value [mM]
38	KM Value [mM]
25	Localization
14	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
345	Organism
50	Pathway
285	PDB ID
8	pH Optimum
1	pH Range
2	pI Value
3	Posttranslational Modification
20	Protein Variants
15	Purification (Commentary)
4	Reaction
6	Reaction Type
63	Reference
1	Renatured (Commentary)
22	Source Tissue
10	Specific Activity [micromol/min/mg]
1	Storage Stability
104	Substrates and Products (Substrate)
18	Subunits
129	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Temperature Stability [°C]
28	Turnover Number [1/s]

KI Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KI Value on EC 4.2.1.17 - enoyl-CoA hydratase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Ki Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.037

(3S)-hydroxybutanoyl-CoA

Bos taurus

-

pH 8, 25°C

33718

0.00035

(3S)-hydroxyhexadecanoyl-CoA

Bos taurus

-

pH 8, 25°C

33718

0.041 - 0.0492

(R)-methylenecyclopropylformyl-CoA

4 entries

0.053 - 0.0571

(S)-methylenecyclopropylformyl-CoA

2 entries

0.065

3-octynoyl-CoA

Rattus norvegicus

-

ECH2

689308

0.0016 - 0.014

acetoacetyl-CoA

2 entries

0.0003

decenoyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.0004

dodecenoyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.0005

hexadecenoyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.00024

hexenoyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.00028

octenoyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.00042

tetradecenoyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.041

(R)-methylenecyclopropylformyl-CoA

Rattus norvegicus

-

25°C, ECH2

689308

0.047

(R)-methylenecyclopropylformyl-CoA

Rattus norvegicus

-

25°C, ECH1

689308

0.049

(R)-methylenecyclopropylformyl-CoA

Rattus norvegicus

-

25°C, ECH1

689308

0.0492

(R)-methylenecyclopropylformyl-CoA

Rattus norvegicus

-

25°C

689308

0.053

(S)-methylenecyclopropylformyl-CoA

Rattus norvegicus

-

25°C, ECH2

689308

0.0571

(S)-methylenecyclopropylformyl-CoA

Rattus norvegicus

-

25°C

689308

0.0016

acetoacetyl-CoA

Bos taurus

-

pH 7.5, 25°C

33730

0.014

acetoacetyl-CoA

Sus scrofa

-

pH 8.0, due to the binding of the enolate form of acetoacetyl-CoA the Ki-value should be highly pH-dependent

5866