4.2.1.161: bisanhydrobacterioruberin hydratase
This is an abbreviated version!
For detailed information about bisanhydrobacterioruberin hydratase, go to the full flat file.
Reaction
Synonyms
c0505, C50 carotenoid 2'',3''-hydratase, CruF
ECTree
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General Information
General Information on EC 4.2.1.161 - bisanhydrobacterioruberin hydratase
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evolution
malfunction
the deletion mutant strain DELTAc0505 shows the same growth rate as wild-type strain. The main cartotenoid products of the mutant strain are monoanhydrobacterioruberin and bisanhydrobacterioruberin. When plasmid pJc0505 containing the intact c0505 gene is introduced into the DELTAc0507 strain, the transformant restores the production of bacterioruberin
metabolism
C0505, the C50 carotenoid 2'',3''-hydratase from Haloarcula japonica, is a homologue of the CruF-type carotenoid 1,2-hydratase
evolution
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C0505, the C50 carotenoid 2'',3''-hydratase from Haloarcula japonica, is a homologue of the CruF-type carotenoid 1,2-hydratase
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the enzyme is involved in biosynthesis of the C50 carotenoid bacterioruberin
metabolism
the gene cluster, including genes c0507, c0506, and c0505, is involved in the synthesis of bacterioruberin. Genes c0507, c0506, and c0505 encode a carotenoid 3,4-desaturase (CrtD), a bifunctional lycopene elongase and 1,2-hydratase (LyeJ), and a C50 carotenoid 2'',3''-hydratase (CruF), respectively. The three carotenoid biosynthetic enzymes catalyze the reactions that convert lycopene to bacterioruberin in Haloarcula japonica. Biosynthetic pathway of C50 carotenoids, overview
metabolism
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the gene cluster, including genes c0507, c0506, and c0505, is involved in the synthesis of bacterioruberin. Genes c0507, c0506, and c0505 encode a carotenoid 3,4-desaturase (CrtD), a bifunctional lycopene elongase and 1,2-hydratase (LyeJ), and a C50 carotenoid 2'',3''-hydratase (CruF), respectively. The three carotenoid biosynthetic enzymes catalyze the reactions that convert lycopene to bacterioruberin in Haloarcula japonica. Biosynthetic pathway of C50 carotenoids, overview
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