4.2.1.160: 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase
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For detailed information about 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase, go to the full flat file.
Reaction
Synonyms
N-(5'-phosphoribosyl)anthranilate isomerase/dehydratase, TrpFCtL2
ECTree
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General Information
General Information on EC 4.2.1.160 - 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase
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physiological function
enzyme TrpFCtL2, in combination with GTP cyclohydrolase II, i.e. RibA, the first enzyme of riboflavin synthesis, provides a bypass of the first two canonical steps in folate synthesis catalyzed by FolE and FolQ. TrpFCtL2 retains the phosphoribosyl anthranilate isomerase activity of the original annotation
physiological function
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enzyme TrpFCtL2, in combination with GTP cyclohydrolase II, i.e. RibA, the first enzyme of riboflavin synthesis, provides a bypass of the first two canonical steps in folate synthesis catalyzed by FolE and FolQ. TrpFCtL2 retains the phosphoribosyl anthranilate isomerase activity of the original annotation
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