4.2.1.157: (R)-2-hydroxyisocaproyl-CoA dehydratase
This is an abbreviated version!
For detailed information about (R)-2-hydroxyisocaproyl-CoA dehydratase, go to the full flat file.
Word Map on EC 4.2.1.157
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4.2.1.157
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mycolic
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hadab
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tuberculosis
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fas-ii
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ketyl
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difficile
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clostridia
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2-hydroxyacyl-coa
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thiacetazone
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antitubercular
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isoxyl
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nitrogenase
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3-hydroxyacyl
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2-hydroxyglutaryl-coa
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benzoyl-coa
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oxygen-sensitive
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fermentans
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acidaminococcus
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symbiosum
- 4.2.1.157
-
mycolic
-
hadab
- tuberculosis
- fas-ii
-
ketyl
- difficile
- clostridia
-
2-hydroxyacyl-coa
- thiacetazone
-
antitubercular
- isoxyl
- nitrogenase
-
3-hydroxyacyl
-
2-hydroxyglutaryl-coa
- benzoyl-coa
-
oxygen-sensitive
- fermentans
-
acidaminococcus
- symbiosum
Reaction
Synonyms
2-hydroxyisocaproyl-CoA dehydratase, HadBC, HadBC dehydratase
ECTree
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Reference
Reference on EC 4.2.1.157 - (R)-2-hydroxyisocaproyl-CoA dehydratase
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Knauer, S.H.; Buckel, W.; Dobbek, H.
On the ATP-dependent activation of the radical enzyme (R)-2-hydroxyisocaproyl-CoA dehydratase
Biochemistry
51
6609-6622
2012
Clostridioides difficile (Q5U925), Clostridioides difficile
Kim, J.; Darley, D.; Buckel, W.
2-Hydroxyisocaproyl-CoA dehydratase and its activator from Clostridium difficile
FEBS J.
272
550-561
2005
Clostridioides difficile (Q5U923 and Q5U924), Clostridioides difficile
Knauer, S.H.; Buckel, W.; Dobbek, H.
Structural basis for reductive radical formation and electron recycling in (R)-2-hydroxyisocaproyl-CoA dehydratase
J. Am. Chem. Soc.
133
4342-4347
2011
Clostridioides difficile (Q5U923 and Q5U924), Clostridioides difficile
Kim, J.; Lu, Y.; Buckel, W.
ATP- and redox-induced conformational changes in the activator of the radical enzyme 2-hydroxyisocaproyl-CoA dehydratase
C. R. Chimie
10
742-747
2007
Clostridioides difficile
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Kim, J.; Pierik, A.; Buckel, W.
A complex of 2-hydroxyisocaproyl-Coenzyme A dehydratase and its activator from clostridium difficile stabilized by aluminium tetrafluoride-adenosine diphosphate
Chemphyschem
11
1307-1312
2010
Clostridioides difficile
Slama, N.; Jamet, S.; Frigui, W.; Pawlik, A.; Bottai, D.; Laval, F.; Constant, P.; Lemassu, A.; Cam, K.; Daffe, M.; Brosch, R.; Eynard, N.; Quemard, A.
The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis
Mol. Microbiol.
99
794-807
2016
Mycobacterium tuberculosis, Mycobacterium tuberculosis (I6WYY7 AND P9WFJ9), Mycobacterium tuberculosis ATCC 25618/ H37Rv (I6WYY7 AND P9WFJ9), Mycobacterium tuberculosis ATCC 25177 / H37Ra
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