4.2.1.157: (R)-2-hydroxyisocaproyl-CoA dehydratase
This is an abbreviated version!
For detailed information about (R)-2-hydroxyisocaproyl-CoA dehydratase, go to the full flat file.
Word Map on EC 4.2.1.157
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4.2.1.157
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mycolic
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hadab
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tuberculosis
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fas-ii
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ketyl
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difficile
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clostridia
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2-hydroxyacyl-coa
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thiacetazone
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antitubercular
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isoxyl
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nitrogenase
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3-hydroxyacyl
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2-hydroxyglutaryl-coa
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benzoyl-coa
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oxygen-sensitive
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fermentans
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acidaminococcus
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symbiosum
- 4.2.1.157
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mycolic
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hadab
- tuberculosis
- fas-ii
-
ketyl
- difficile
- clostridia
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2-hydroxyacyl-coa
- thiacetazone
-
antitubercular
- isoxyl
- nitrogenase
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3-hydroxyacyl
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2-hydroxyglutaryl-coa
- benzoyl-coa
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oxygen-sensitive
- fermentans
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acidaminococcus
- symbiosum
Reaction
Synonyms
2-hydroxyisocaproyl-CoA dehydratase, HadBC, HadBC dehydratase
ECTree
4.2.1.157 (R)-2-hydroxyisocaproyl-CoA dehydrataseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 4.2.1.157 - (R)-2-hydroxyisocaproyl-CoA dehydratase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(R)-2-hydroxy-4-methylpentanoyl-CoA
4-methylpent-2-enoyl-CoA + H2O
i.e. (R)-2-hydroxyisocaproyl-CoA. The enzyme is involved in the reductive branch of L-leucine fermentation
i.e. isocaprenoyl-CoA
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?
(R)-2-hydroxy-4-methylpentanoyl-CoA
4-methylpent-2-enoyl-CoA + H2O
the enzyme is involved in fermentation of L-leucine
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?
(R)-2-hydroxy-4-methylpentanoyl-CoA
4-methylpent-2-enoyl-CoA + H2O
Mycobacterium tuberculosis ATCC 25177 / H37Ra
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-
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?
(R)-2-hydroxy-4-methylpentanoyl-CoA
4-methylpent-2-enoyl-CoA + H2O
Mycobacterium tuberculosis ATCC 25618/ H37Rv
I6WYY7; P9WFJ9
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-
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?
additional information
?
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1H-NMR analysis of the unsaturations in the mycolic acid of different Mycobacterium tuberculosis wild-type and mutant strains, overview
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?
additional information
?
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I6WYY7; P9WFJ9
1H-NMR analysis of the unsaturations in the mycolic acid of different Mycobacterium tuberculosis wild-type and mutant strains, overview
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-
?
additional information
?
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Mycobacterium tuberculosis ATCC 25177 / H37Ra
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1H-NMR analysis of the unsaturations in the mycolic acid of different Mycobacterium tuberculosis wild-type and mutant strains, overview
-
-
?
additional information
?
-
Mycobacterium tuberculosis ATCC 25618/ H37Rv
I6WYY7; P9WFJ9
1H-NMR analysis of the unsaturations in the mycolic acid of different Mycobacterium tuberculosis wild-type and mutant strains, overview
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-
?
